ArticleOncology letters2026
CANT1 as a novel prognostic biomarker in triple-negative breast cancer.
Article in Oncology letters, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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12 authors.
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Abstract
Triple-negative breast cancer (TNBC) is one of the most aggressive breast cancer subtypes, with limited targeted treatment options and poor clinical outcomes. Calcium-activated nucleotidase 1 (CANT1), a calcium dependent enzyme involved in nucleotide metabolism and glycoprotein processing, has attracted limited attention in oncology and its clinical relevance in breast cancer remains unknown. The present study hypothesized that CANT1 expression may carry prognostic information in TNBC and evaluated its association with clinicopathologicalal features and survival. In the present retrospective study, 59 non-metastatic patients with TNBC who underwent curative surgery were included. CANT1 expression was assessed using immunohistochemistry and semiquantitatively scored using an H-score ranging from 1-300. Patients were categorized into three groups according to H-score (H1, 1-100; H2, 101-200; H3, 201-300). Associations between CANT1 expression and clinicopathologicalal variables were analyzed using the χ
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