Evidence map›Paper›PMID 41858373›Full record

ArticleOncology letters2026

Telomere maintenance mechanisms are activated in ganglioneuroblastoma and ganglioneuroma.

Motoki Sugawara, Masayuki Haruta, Miki Ohira, Jesmin Akter, Ritsuko Onuki, Ryuichi P Sugino, Kiyohiro Ando, Atsuko Nakazawa, Hajime Okita, Tetsuya Takimoto and 4 more

Abstract read
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In one paragraph

Article in Oncology letters, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Motoki SugawaraResearch Institute for Clinical Oncology, Saitama Cancer Center, Ina, Saitama 362-0806, Japan.
Masayuki HarutaResearch Institute for Clinical Oncology, Saitama Cancer Center, Ina, Saitama 362-0806, Japan.
Miki OhiraResearch Institute for Clinical Oncology, Saitama Cancer Center, Ina, Saitama 362-0806, Japan.
Jesmin AkterResearch Institute for Clinical Oncology, Saitama Cancer Center, Ina, Saitama 362-0806, Japan.
Ritsuko OnukiResearch Institute for Clinical Oncology, Saitama Cancer Center, Ina, Saitama 362-0806, Japan.
Ryuichi P SuginoResearch Institute for Clinical Oncology, Saitama Cancer Center, Ina, Saitama 362-0806, Japan.
Kiyohiro AndoResearch Institute for Clinical Oncology, Saitama Cancer Center, Ina, Saitama 362-0806, Japan.
Atsuko NakazawaDepartment of Clinical Research, Saitama Children's Medical Center, Saitama 330-8777, Japan.
Hajime OkitaDivision of Diagnostic Pathology, Keio University School of Medicine, Tokyo 160-8582, Japan.
Tetsuya TakimotoDepartment of Cancer Data Management, National Center for Child Health and Development, Tokyo 157-8535, Japan.
Tomoko IeharaDepartment of Pediatrics, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto 602-8566, Japan.
Tsugumichi KoshinagaDepartment of Pediatric Surgery, Nihon University School of Medicine, Tokyo 173-8610, Japan.
Shuichiro UeharaDepartment of Pediatric Surgery, Nihon University School of Medicine, Tokyo 173-8610, Japan.
Takehiko KamijoResearch Institute for Clinical Oncology, Saitama Cancer Center, Ina, Saitama 362-0806, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Telomere maintenance mechanisms (TMM) have garnered attention as a mechanism associated with the treatment resistance and poor prognosis of neuroblastoma (NB). Ganglioneuroblastoma (GNB) and ganglioneuroma (GN) are histologically classified as neuroblastic tumors (NTs) along with NB; however, few reports have addressed TMM in GNB and GN. The present study analyzed 321 NTs diagnosed in Japan, including 255 NB cases, 48 GNB cases and 18 GN cases, using a quantitative PCR-based C-circle assay for alternative lengthening of telomeres (ALT) and a telomerase reverse transcriptase (

Indexed as

GNGNBNBNTsTMM

Identifiers

PMID41858373
PMCPMC12997032

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.