Evidence map›Paper›PMID 41858340›Full record

SynthesisFrontiers in oncology2026

Natural medicines for radioprotection and radiosensitization: a bibliometric analysis of mechanisms and trends (2001-2025).

Yupeng Di, Jiazhao Song, Yingjie Wang, Lingling Meng, Jing Li

Abstract readSystematic Review
In one paragraph

Synthesis in Frontiers in oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yupeng Di *Department of radiation protection medicine, School of Preventive Medicine, Fourth Military Medical University, Xi'an, China.
Jiazhao Song *Experimental Tumorpathology, University Hospital Erlangen, Friedrich-Alexander-Universitat Erlangen-Nurnberg, Erlangen, Germany.
Yingjie WangDepartment of Radiation Oncology, Air Force Medical Center, People's Liberation Army, Beijing, China.
Lingling MengDepartment of Radiation Oncology, Senior Department of Oncology, The First Medical Center of People's Liberation Army General Hospital, Beijing, China.
Jing LiDepartment of radiation protection medicine, School of Preventive Medicine, Fourth Military Medical University, Xi'an, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Ionizing radiation (IR) poses a global health threat, inducing molecular damage and chronic issues. Despite its significance, there has been limited bibliometric analysis to systematically evaluate the status, hotspots, and trends in the field of natural medicines (NMs) against IR. Purpose: To comprehensively understand the status, hotspots, and trends in the field of NMs against IR. Methods: Documents concerning NMs against IR were extracted from the Web of Science Core Collection (WoSCC) and PubMed databases. The literature analysis was conducted using VOSviewer 1.6.17 and CiteSpace 6.1.R6 software. Results: In total, 450 publications were encompassed. The most productive author was Baliga MS (19 documents) and Father Muller Medical College (11 documents, 688 citations); dominant countries were India (148 documents) and Peoples R China (99 documents); and a top journal was J Ethnopharmacol (615 citations). The first high-cited article was "Protection against Ionizing Radiation by Antioxidant Nutrients and Phytochemicals" by Weiss, JF (2003) with 459 citations. Oxidative stress, DNA damage, apoptosis, and radioprotection were identified as core research themes. Conclusion: Currently, the main hotspot is the elucidation of cellular and molecular mechanisms using novel technologies such as network pharmacology, molecular docking, and experimental validation. Future studies are needed to focus on the inherent molecular mechanisms and clinical applications. In addition, potential side effects of the bioactive compounds cannot be ignored.

Indexed as

bibliometric analysisionizing radiationmolecular mechanismsnatural medicinesradioprotectionradiosensitization

Identifiers

PMID41858340
PMCPMC12995765

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.