ArticleJournal of cosmetic dermatology2026
Application of Brachytherapy in Postoperative Treatment of Keloid-Prone Patients.
Article in Journal of cosmetic dermatology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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3 authors.
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Abstract
backgroundKeloids are benign fibroproliferative tumors that often recur after surgical excision. Combining surgery with postoperative radiotherapy has emerged as a potential treatment strategy, though optimal radiotherapy protocols remain debated.
objectiveThis study aims to preliminarily evaluate the efficacy and safety of a single high-dose brachytherapy session administered within 8 h after surgical excision in keloid-prone patients in a retrospective setting.
methodsA retrospective case series analysis was conducted on 32 patients who underwent surgical excision of keloids followed by a single 8 Gy Ir-192 brachytherapy session within 8 h postoperatively. Treatment outcomes and adverse reactions were assessed over a 1-year follow-up period.
resultsAmong the 32 patients, 25 were cured, 5 showed significant improvement, and 2 were ineffective, yielding a total effective rate of 93.75%. No severe radiation-induced skin reactions (Grade III/IV) or abnormalities in thyroid or estrogen levels were observed.
conclusionIn this small retrospective series, single-dose 8 Gy brachytherapy administered within 8 h after surgical excision was associated with a high response rate and no severe adverse events. These findings suggest it may be a potentially useful outpatient treatment option for keloids, though further comparative studies are needed to confirm its efficacy and safety.
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