ArticleBMJ open2026
Latent profile analysis and influencing factors of engagement in medication safety among older adults with cardiometabolic multimorbidity: a cross-sectional study.
Article in BMJ open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
objectiveThis study aims to explore the latent profiles and influencing factors of engagement in medication safety among elderly patients with cardiometabolic multimorbidity.
designA cross-sectional study.
settingThe study was conducted at a class III hospital in Jiangsu, China.
participantsThe study included a sample of 316 older adult inpatients with cardiometabolic multimorbidity. OUTCOME MEASURES: Participants completed the Inpatients' Involvement in Medication Safety Scale and the Multimorbidity Treatment Burden Questionnaire. Latent profile and multivariate regression analyses were used to identify subgroups and their associated factors.
resultsLatent profile analysis identified three distinct profiles: 'passive participation' (22.47%), 'moderate participation' (52.53%) and 'active participation' (25.0%). Multivariate logistic regression revealed that occupational status, marital status, medical payment method, daily medication type and treatment burden were significant independent factors distinguishing among these profiles (p<0.05).
conclusionsThe study confirms significant heterogeneity in medication safety engagement among older adults with cardiometabolic multimorbidity. The identified profiles and their specific influencing factors provide a basis for clinicians to stratify patients and develop targeted interventions, particularly for the vulnerable 'passive participation' group, to improve medication safety outcomes.
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