Evidence map›Paper›PMID 41857780›Full record

ArticleJournal of health, population, and nutrition2026

Impact of BCNSP-led parenteral nutrition management on prescribing errors in the neonatal intensive care unit.

Gul Ambreen, Zainab Bibi, Aysha Sultan, Rabia Munir, Amin Ali, Manoj Kumar, Ijaz Hussain, Hafiz Muhammad Aamir Yousuf, Muhammad Sohail Salat, Saeed Ahmed and 2 more

Abstract readComparative Study
In one paragraph

Article in Journal of health, population, and nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

12 authors.

Gul AmbreenDepartment of Pediatrics and Child Health, Aga Khan University Hospital, Karachi, Pakistan. gul.ambreen@aku.edu.ORCID 0000-0002-6287-6898
Zainab BibiDepartment of Pediatrics and Child Health, Aga Khan University Hospital, Karachi, Pakistan.
Aysha SultanNational Institute of Child Health, Karachi, Pakistan.
Rabia MunirDepartment of Pediatrics and Child Health, Aga Khan University Hospital, Karachi, Pakistan.
Amin AliDow University of Health Sciences, Karachi, Pakistan.
Manoj KumarDepartment of Pediatrics and Child Health, Aga Khan University Hospital, Karachi, Pakistan.
Ijaz HussainDepartment of Pediatrics and Child Health, Aga Khan University Hospital, Karachi, Pakistan.
Hafiz Muhammad Aamir YousufDepartment of Pediatrics and Child Health, Aga Khan University Hospital, Karachi, Pakistan.
Muhammad Sohail SalatDepartment of Pediatrics and Child Health, Aga Khan University Hospital, Karachi, Pakistan.
Saeed AhmedDepartment of Pediatrics and Child Health, Aga Khan University Hospital, Karachi, Pakistan.
Ayaz Ur RehmanDepartment of Pediatrics and Child Health, Aga Khan University Hospital, Karachi, Pakistan.
Kashif HussainDepartment of Pharmacy, Aga Khan University Hospital, Karachi, Pakistan. kashif.hussain@aku.edu.ORCID 0000-0001-9836-1696

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundParenteral nutrition (PN) preparations are listed as high-alert medications and have a high probability of medication errors (MEs). Board-certified Nutrition Support Pharmacists (BCNSPs) can play an important role in reducing PN-associated complications by highlighting the gaps in the PN prescribing process. This study aimed to determine the impact of BCNSP-led PN review on the identification and documentation of prescribing MEs (PMEs) to optimize quality and safety in PN prescribing processes.

methodsThis QI quasi-experimental study included all neonates admitted to a level III neonatal intensive care unit (NICU) and prescribed PN. All identified and recognized PN-PMEs documented by pharmacists were evaluated in pre-and post-implementation-phases. In the pre-phase, the PN-duty pharmacist reviewed all the neonatal PN-orders while located in the pharmacy, and in the post-phase, a clinically involved BCNSP performed this task. All PN-PMEs were categorized into ten types. Predictors of PN-PMEs were analyzed through logistic regression.

resultsPN-orders were prescribed to 98 and 112 neonates in pre-and post-phases, respectively. For demographic and clinical variables, neonates were comparable. A median of 12 (range = 9 - 19) vs. 15 (range = 12-22) PN-orders/day were reviewed in pre-and post-phases. Documented PN-PMEs for all PN orders were significantly higher in the post-phase (212/2577, 8.23%) compared with the pre-phase (25/2577, 0.97%; p < 0.001). "Wrong Dose/Calculation" was the most reported category (88/2577, 3.41%). "Wrong concentration range" was the second highest (29/1309, 2.22%) and all were reported only in post-phase. Additional errors involved infusion, compatibility, and osmolarity deviations, renal/hepatic dose adjustment errors and stability errors. Most of them were only identified in the post-phase. Post-phase outcomes showed clinically meaningful reductions in metabolic derangements, NICU stay, and mortality (p < 0.001).

conclusionThe engagement of BCNSPs in the clinical neonatal setting for PN management may improve the safety and efficacy of PN-therapy.

Indexed as

Health Plan ImplementationMedication ErrorsMedication ReviewParenteral NutritionPharmacistsFemaleHumansInfant, NewbornIntensive Care Units, NeonatalMaleNon-Randomized Controlled Trials as TopicQuality ImprovementBCNSPBoard certified nutrition support pharmacistMedication errorsNeonatal careNeonatesNICUParenteral nutritionPatient safetyPharmacist

Identifiers

PMID41857780
PMCPMC13020413

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.