ArticleJournal of nanobiotechnology2026
Coupled mesoporous silica nanoparticles and limonene-chitosan Pickering emulsions: enhanced insecticidal delivery and selectivity.
Article in Journal of nanobiotechnology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
backgroundNanodelivery represents a promising strategy to enhance pesticide efficacy while reducing associated environmental risks. Mesoporous silica nanospheres (MSNs) can serve as effective nanocarriers but improvements are essential in terms of targeting and efficiency. A promising approach involves combining nanocarriers-mediated pesticide delivery system with bioactive compounds, in which the compounds act as synergist that can disrupt insect defence mechanisms. Pickering emulsions (PEs) offer significant advantages in improving the bioavailability of active ingredients from compounds, which would enhance the synergistic effect to insecticides. Beyond encapsulating bioactive compounds, PEs serve as efficient pesticide delivery vehicles, enhancing leaf wettability and foliar deposition, making them effective adjuvants. This study aimed to construct a hybrid platform that integrates pesticides-loaded MSNs with synergistic PE as adjuvants, developing porous nanocarrier-based nanoemulsions to fight against insecticide-resistant pests.
resultsThe nanosystem (IMI@MSNs@lim@chs) that integrates imidacloprid (IMI)-loaded MSNs with limonene-chitosan (lim@chs) Pickering emulsions as adjuvants was developed and successfully control the resistance agroforestry pests, Myzus persicae (Sulzer). The IMI@MSNs complex showed increased toxicity than IMI, which account for the pesticide absorption and delivery capacity of MSNs. While incorporation IMI@MSNs with lim@chs, the IMI@MSNs@lim@chs nanosystem achieved the highest efficacy, indicating the remarkable synergistic effect of the lim@chs adjuvant. Mechanistic analyses have demonstrated that the lim@chs enhanced IMI activity was attributed to remarkable antibacterial effects, hydrophobicity, and lipophilicity, which suppress P450-mediated detoxification by inducing gut microbiota deficiency and facilitating epidermal penetration via cuticle disruption. In parallel, the porous MSNs promote nanosystem adhesion, preventing run-off and improving the IMI recovery rate after leaching. The lipophilic lim@chs enhances leaf wettability via supramolecular interactions, benefiting droplet rebound and promoting foliar deposition. Importantly, IMI@MSNs@lim@chs exhibits reduced toxicity and minimal impact on the predation capacity of Coccinella septempunctat, demonstrating the lower environmental risks.
conclusionsThe findings of this study demonstrate an effective synergistic coupling of porous nanocarriers with Pickering emulsions as adjuvants to enhance pesticide delivery and selectivity, offering a promising platform for sustainable pest management.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.