Evidence map›Paper›PMID 41857611›Full record

ArticleVeterinary research2026

A safe and efficacious inactivated vaccine aids prevent reproductive failure associated with congenital toxoplasmosis in ovine.

Javier Regidor-Cerrillo, Andrea Largo-de la Torre, Roberto Sánchez-Sánchez, Ignacio Ferre, Javier Moreno-Gonzalo, Luis Miguel Ortega-Mora

Abstract read
In one paragraph

Article in Veterinary research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Veterinary sciences · 2026
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Javier Regidor-CerrilloSALUVET-Innova, Faculty of Veterinary Sciences, Complutense University of Madrid, Ciudad Universitaria s/n, 28040, Madrid, Spain. jregidor.saluvetinnova@gmail.com.
Andrea Largo-de la TorreSALUVET-Innova, Faculty of Veterinary Sciences, Complutense University of Madrid, Ciudad Universitaria s/n, 28040, Madrid, Spain.
Roberto Sánchez-SánchezSALUVET, Animal Health Department, Faculty of Veterinary Sciences, Complutense University of Madrid, Ciudad Universitaria s/n, 28040, Madrid, Spain.
Ignacio FerreSALUVET, Animal Health Department, Faculty of Veterinary Sciences, Complutense University of Madrid, Ciudad Universitaria s/n, 28040, Madrid, Spain.
Javier Moreno-GonzaloSALUVET, Animal Health Department, Faculty of Veterinary Sciences, Complutense University of Madrid, Ciudad Universitaria s/n, 28040, Madrid, Spain.
Luis Miguel Ortega-MoraSALUVET, Animal Health Department, Faculty of Veterinary Sciences, Complutense University of Madrid, Ciudad Universitaria s/n, 28040, Madrid, Spain. luis.ortega@ucm.es.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Toxoplasma gondii is an apicomplexan parasite causing reproductive failure in small ruminants. In this study, we evaluated the capacity of an inactivated vaccine to prevent reproductive failure caused by congenital toxoplasmosis in sheep. The vaccine is based on an antigen extract obtained from a low passage T. gondii Type III isolate (TgPigSp1) preserving the ability to spontaneously produce cysts in vitro and following a procedure involving parasite inactivation via hyperosmotic shock and membrane proteins solubilisation. The vaccine prototype, consisting of 40 µg of parasite extract adjuvanted with QuilA

Indexed as

Abortion, VeterinaryProtozoan VaccinesSheep DiseasesToxoplasmaToxoplasmosis, AnimalToxoplasmosis, CongenitalAnimalsFemalePregnancySheepSheep, DomesticVaccines, InactivatedProtozoan VaccinesVaccines, Inactivatedcongenital toxoplasmosisimprovement of reproductive lossesmultistage vaccinereproductive failureSheep

Identifiers

PMID41857611
PMCPMC13003711

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.