ArticleTrials2026
Addressing laboratory challenges in clinical trials: approaches from the Clinical Diagnostic Laboratory Services at MRC/UVRI and LSHTM Uganda Research Unit.
Article in Trials, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
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Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Laboratories can play a critical role in the conduct of clinical trials. Management of different aspects of the clinical laboratory processes is essential and can determine the success of a trial. Activities within the laboratory process encompassing pre-analytical, analytical, and post-analytical processes ought to be thoroughly monitored. In this paper, we present an outline of approaches for sample collection, sample transport, sample storage, sample analysis, and data management, in a laboratory setting. The paper highlights that clinical trials are more likely to be completed successfully if there is rigorous adherence to organized quality management approaches in the laboratory. We also discuss the challenges encountered that include sample quality issues, equipment downtime, absence of reference ranges generated from the local population among others, and approaches implemented to overcome these. If implemented, the approaches described here are expected to improve the quality and integrity of the data produced in laboratories which in turn will contribute to successful clinical trial conduct.
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Registered trials
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