Evidence map›Paper›PMID 41857585›Full record

SynthesisBMC oral health2026

Prevalence and associated risk indicators of early childhood caries in Nigeria: a systematic review and meta-analysis.

Enameguolo Eureka Orhorhoro, Nneka Maureen Chukwumah, Opeoluwa Adewale, Nneka Kate Onyejaka, Adebola Oluyemisi Ehizele, Folahanmi Tomiwa Akinsolu, George Uchenna Eleje, Oliver Chukwujekwe Ezechi, Moréniké Oluwátóyìn Foláyan

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in BMC oral health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Enameguolo Eureka OrhorhoroDepartment of Paediatric Dentistry, University of Benin Teaching Hospital, Benin City, 300001, Nigeria. eurekaseries@gmail.com.ORCID 0009-0009-4659-6958
Nneka Maureen ChukwumahDepartment of Paediatric Dentistry, University of Benin Teaching Hospital, Benin City, 300001, Nigeria.
Opeoluwa AdewaleFirst Mobile Dental Clinic, Yaba, Lagos, Nigeria.
Nneka Kate OnyejakaDepartment of Child Dental Health, Faculty of Dentistry, College of Medicine, University of Nigeria, Ituku-Ozalla, Enugu, Nigeria.
Adebola Oluyemisi EhizeleDepartment of Periodontics, School of Dentistry, College of Medical Sciences, University of Benin, Benin City, 300001, Nigeria.
Folahanmi Tomiwa AkinsoluLead University, Ibadan, Oyo, Nigeria.
George Uchenna ElejeDepartment of Obstetrics and Gynaecology, Nnamdi Azikiwe University, Awka, Anambra, Nigeria.
Oliver Chukwujekwe EzechiNigerian Institute of Medical Research, Yaba, Lagos, Nigeria.
Moréniké Oluwátóyìn FoláyanOral Health Initiative, Nigerian Institute of Medical Research, Yaba, Lagos, Nigeria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEarly childhood caries (ECC) is a disease of global public health significance and a source of concern, especially in resource-poor countries like Nigeria. This study aims to determine the prevalence and associated risk indicators for ECC in Nigeria.

methodsThis systematic review protocol for this systematic review was registered on PROSPERO (CRD420250654057). A systematic search of PubMed, Web of Science, African Journals Online, Scopus, ProQuest, and Directory of Open Access Journals was conducted from inception to April 1, 2025, for studies reporting the prevalence of ECC and its risk indicators in children in Nigeria aged 0–71 months. Grey literature was sought from the Nigeria and West Africa Postgraduate Medical Colleges. Eligible studies included peer-reviewed articles, conference proceedings, government and international organization reports, and unpublished studies. Quality was assessed using the Joanna Briggs Institute checklist. A random effect model was used to calculate the pooled prevalence, and sensitivity and subgroup analysis were performed to explore heterogeneity.

resultsThirty-one studies published between 2006 and 2025 were included in the systematic review, and 27 in the meta-analysis. The pooled prevalence of ECC was 22% (95% CI: 17–26%; I²=98%), decreasing to 19% (95% CI: 15–23) after the sensitivity analysis. Subgroup analysis revealed no significant difference in the prevalence over time (p = 0.060) or by sex (females slightly higher, p = 0.720). Regional prevalence was highest in the Northeast and Southwest (p < 0.001), children from high-income groups had the highest ECC prevalence (p = 0.030), and prevalence increased significantly with age (p < 0.001).

conclusionApproximately one in every five children in Nigeria has ECC, indicating a substantial burden. These findings underscore the need for sustained preventive strategies and have significant implications for oral health policy and practice in Nigeria. REGISTRATION: Registered on PROSPERO on 24th February 2025 with registration number: CRD420250654057.

Indexed as

Dental CariesChild, PreschoolHumansInfantInfant, NewbornNigeriaPrevalenceRisk FactorsCaries experienceDental cariesEarly childhood cariesPrevalenceRisk indicator

Identifiers

PMID41857585
PMCPMC13217678

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.