Evidence map›Paper›PMID 41857507›Full record

ArticleBMC plant biology2026

A circadian repressor promotes flowering via dual repression: PtTOC suppresses the floral inhibitor PtTFL2 in Pinus tabuliformis.

Kai Qu, Huili Wang, Boning Yang, Shihui Niu, Hua Xue, Yousry A El-Kassaby, Wei Li

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC plant biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Kai Qu *State Key Laboratory of Tree Genetics and Breeding, National Engineering Research Center of Tree Breeding and Ecological Restoration, College of Biological Sciences and Technology, Beijing Forestry University, Beijing, 100083, China.
Huili Wang *State Key Laboratory of Tree Genetics and Breeding, National Engineering Research Center of Tree Breeding and Ecological Restoration, College of Biological Sciences and Technology, Beijing Forestry University, Beijing, 100083, China.
Boning YangCollege of Forestry, Southwest Forestry University, Kunming, 650224, China.
Shihui NiuState Key Laboratory of Tree Genetics and Breeding, National Engineering Research Center of Tree Breeding and Ecological Restoration, College of Biological Sciences and Technology, Beijing Forestry University, Beijing, 100083, China.
Hua XueState Key Laboratory of Tree Genetics and Breeding, National Engineering Research Center of Tree Breeding and Ecological Restoration, College of Biological Sciences and Technology, Beijing Forestry University, Beijing, 100083, China.
Yousry A El-KassabyDepartment of Forest and Conservation Sciences, Faculty of Forestry, University of British Columbia, Vancouver, British Columbia, V6T 1Z4, Canada.
Wei LiState Key Laboratory of Tree Genetics and Breeding, National Engineering Research Center of Tree Breeding and Ecological Restoration, College of Biological Sciences and Technology, Beijing Forestry University, Beijing, 100083, China. bjfuliwei@bjfu.edu.cn.

Funding

National Key R&D Plan for the Fourteenth Five Year Plan 2023YFD2200605-3
6 · The paper itself

Abstract

The Response Regulator (RR) gene family functions as a molecular “switch” in plant signal transduction, with TOC1 (PRR1) frequently acting as a transcriptional repressor that integrates both internal and external signals. While RR homologs in gymnosperms differ from those in angiosperms, research on their function remains sparse. This study presents a genome-wide analysis of the RR gene family in Pinus tabuliformis, identifying 35 RR genes that are grouped into three subfamilies: A-type ARRs (17 genes), B-type ARRs (16 genes), and pseudo-RRs (2 genes). Except for PtPRR43, these genes are distributed across various chromosomes, with 16 displaying broad expression in multiple organs. Our findings revealed that PtTOC indirectly promotes flowering by suppressing PtTFL2, a floral repressor, suggesting its role in balancing circadian rhythms and environmental signals. Additionally, PtTOC overexpression reduces cold tolerance, likely through the downregulation of cold-responsive pathways, suggesting a trade-off between promoting flowering and stress resilience. Subcellular localization analysis suggests PtTOC undergoes phosphorylation-regulated phase transitions, highlighting its dynamic role in cellular signaling and adaptation. Collectively, these results position PtTOC as a central integrator of environmental signals and circadian regulation, offering insights into strategies for enhancing reproductive performance and resilience in gymnosperms.

Indexed as

Circadian RhythmFlowersPinusPlant ProteinsGene Expression Regulation, PlantPlant ProteinsPinus tabuliformisPromoting floweringResponse regulator gene familyTIMING OF CAB EXPRESSION 1Transcriptional repressor

Identifiers

PMID41857507
PMCPMC13123111

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.