Evidence map›Paper›PMID 41857501›Full record

ArticleBMC primary care2026

Nurse-led risk-based primary healthcare intervention in midlife women's health management in Hong Kong: a stepped-wedge cluster randomized controlled trial protocol.

Yushen Zuo, Yee Tak Derek Cheung, Tsz Hong Ryder Chan, Minjin Zhang, Guowen Zhang, Wanjia He, Man Ping Kelvin Wang, Tzu Tsun Kevin Luk, Siu Chee Sophia Chan

Registry-linked trialAbstract readClinical Trial Protocol
In one paragraph

Article in BMC primary care, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06628388 (Nurse-led Primary Healthcare Intervention Model in Women's Health Management in Hong Kong), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06628388 naactive not recruitingnot on this map

Nurse-led Primary Healthcare Intervention Model in Women's Health Management in Hong Kong

TypeinterventionalSponsorThe University of Hong KongRan2024 to 2027Enrolled1,728ConditionsVasomotor Symptoms, Urinary Incontinence, Anxiety, Depression - Major Depressive DisorderArmsNurse-Led Risk-Based 5As Primary Healthcare Model, Minimal Intervention
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yushen ZuoSchool of Nursing, The University of Hong Kong, Hong Kong Special Administrative Region, People's Republic of China.
Yee Tak Derek CheungSchool of Nursing, The University of Hong Kong, Hong Kong Special Administrative Region, People's Republic of China.
Tsz Hong Ryder ChanSchool of Public Health, The University of Hong Kong, Hong Kong Special Administrative Region, People's Republic of China.
Minjin ZhangSchool of Public Health, The University of Hong Kong, Hong Kong Special Administrative Region, People's Republic of China.
Guowen ZhangSchool of Nursing, The University of Hong Kong, Hong Kong Special Administrative Region, People's Republic of China.
Wanjia HeSchool of Public Health, The University of Hong Kong, Hong Kong Special Administrative Region, People's Republic of China.
Man Ping Kelvin WangSchool of Nursing, The University of Hong Kong, Hong Kong Special Administrative Region, People's Republic of China.
Tzu Tsun Kevin LukSchool of Nursing, The University of Hong Kong, Hong Kong Special Administrative Region, People's Republic of China.
Siu Chee Sophia ChanSchool of Public Health, The University of Hong Kong, Hong Kong Special Administrative Region, People's Republic of China. nssophia@hku.h.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMidlife women are facing many healthcare challenges, including unmet needs in screening and preventive care. Nurse-led risk-based model in primary healthcare settings prioritizes preventive care and self-management, potentially increases the use of preventive health services including timely health screenings, chronic disease management and mental health programs, and adequate medical consultations. This study aims to evaluate the effectiveness of a nurse-led risk-based women’s health intervention in enhancing preventive health service utilization and its impacts on self-management, health confidence, quality of life, thereby strengthening primary healthcare for midlife women in the Hong Kong.

methodsA stepped-wedge cluster randomized controlled trial in continuous recruitment will be conducted in three social service organizations, each with four exposure phases and a transition period. A total of 1728 eligible women residents aged 45–64 will be enrolled. Participants allocated to the intervention condition will receive the nurse-led risk-based 5As intervention at baseline, 1, 3, and 6 months follow-up; encompassing assessments, risk stratification, personalized education, consultation, referral, and instant messages. Control condition will include identical assessments and general lifestyle modification advice at baseline, 3 and 6 months follow-up. The primary outcome will be a composite measure of preventive health services utilization (timely screenings, chronic disease management and mental health programs, and relevant medical consultations) at 3 months after the baseline nurse-led consultation. Secondary outcomes will be preventive health services utilization at 6 months after baseline; Health Confidence Scale, Self-Management Assessment Scale, EQ-5D-5L with EQ Visual Analogue Scale, and validated evaluation tools for vasomotor symptoms, urinary incontinence, depression, anxiety, osteoporosis, blood pressure problems, and breast, cervical, colorectal cancer at 3 and 6 months after baseline. Within- and between-group effects over time, interviews of participants and nurses on perceptions and attitudes towards this intervention will be analyzed. DISCUSSION: This study will provide empirical evidence on the effectiveness, feasibility, and acceptability of the nurse-led risk-based 5As intervention targeting women’s health management in primary healthcare. Such intervention, if effective, can be developed as an innovative preventive care model to increase screenings and overall preventive health service utilization, empower women’s capacity in self-health management, and contribute to their health improvements.

trial registrationRegistered in Clinicaltrials.gov (NCT06628388) with study entitled “Nurse-led Primary Healthcare Intervention Model in Women's Health Management in Hong Kong (JCDATAZONEWH)”. Registered on October 4th, 2024.

Indexed as

Preventive Health ServicesPrimary Health CareWomen's HealthFemaleHong KongHumansMiddle AgedQuality of LifeRandomized Controlled Trials as TopicSelf-Management5 A modelHealth services utilizationNurse-ledPreventive carePrimary healthcareRisk stratificationScreeningSelf-managementStepped wedge cluster randomized trialWomen

Identifiers

PMID41857501
PMCPMC13123004

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.