Evidence map›Paper›PMID 41857483›Full record

ArticleJournal of the Chinese Medical Association : JCMA2026

Prenatal depression and psychotropics in offspring asthma and atopic dermatitis.

Li-Chi Chen, Wei-Sheng Huang, Tzeng-Ji Chen, Mu-Hong Chen

Abstract read
In one paragraph

Article in Journal of the Chinese Medical Association : JCMA, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Li-Chi ChenDepartment of Psychiatry, Taipei Veterans General Hospital, Taipei, Taiwan, ROC.
Wei-Sheng HuangDepartment of Psychiatry, Taipei Veterans General Hospital, Taipei, Taiwan, ROC.
Tzeng-Ji ChenDepartment of Family Medicine, Taipei Veterans General Hospital, Taipei, Taiwan, ROC.
Mu-Hong ChenDepartment of Psychiatry, Taipei Veterans General Hospital, Taipei, Taiwan, ROC.ORCID 0000-0001-6516-1073

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe associations of prenatal maternal depression and exposure to antidepressants and benzodiazepines/Z-drugs with the risks of offspring asthma and atopic dermatitis are unclear.

methodsThe data from 1369 child-mother dyads with maternal depression and 13 690 birth year- and sex-matched child-mother dyads without maternal depression for the period from 2002 to 2009 were selected. Prenatal exposure to antidepressants and benzodiazepines/Z-drugs was also considered. All children were followed from their birth date to the end of 2011 to identify the development of asthma and atopic dermatitis.

resultsThe offspring of mothers with depression were more likely to develop atopic dermatitis (hazard ratio [HR], 1.16) and asthma (HR, 1.12) during the follow-up period relative to the control group. Prenatal exposure to benzodiazepines/Z-drugs was strongly associated with an increased risk (HR, 1.27) of offspring asthma. However, prenatal exposure to antidepressants was not associated with increased risks of offspring asthma and atopic dermatitis.

conclusionThe mechanisms underlying the complex relationship between maternal depression, exposure to benzodiazepines/Z-drugs, and the risk of offspring atopy warrant further investigation.

Indexed as

Antidepressive AgentsAsthmaDepressionDermatitis, AtopicPregnancy ComplicationsPrenatal Exposure Delayed EffectsPsychotropic DrugsAdultBenzodiazepinesFemaleHumansMalePregnancyAntidepressive AgentsBenzodiazepinesPsychotropic DrugsAntidepressantsBenzodiazepinesOffspring asthmaOffspring atopic dermatitisPrenatal maternal depression

Identifiers

PMID41857483
PMCPMC13193307

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.