Evidence map›Paper›PMID 41857362›Full record

ArticleEuropean journal of clinical nutrition2026

Association between trajectories of body mass index and changes in fat free mass index and fat mass index in a cohort of European children. The IDEFICS/I.Family studies.

Elizabeth Lizárraga, Iris Iglesia-Altaba, Javier Santabárbara, Wolfgang Ahrens, Claudia Börnhorst, Annarita Formisano, Toomas Veidebaum, Michael Tornaritis, Stefaan De Henauw, Gabriele Eiben and 4 more

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Article in European journal of clinical nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Elizabeth Lizárraga *Medical Faculty. University of Colima. Doctorate in Medical Sciences, Colima, Mexico.ORCID http://orcid.org/0000-0003-1461-5842
Iris Iglesia-Altaba *GENUD (Growth, Exercise, Nutrition and Development) Research Group, Faculty of Health Sciences, Agri-food Institute of Aragón (IA2), University of Zaragoza, Zaragoza, Spain.
Javier SantabárbaraDepartment of Preventive Medicine and Public Health, University of Zaragoza, Zaragoza, Spain.
Wolfgang AhrensLeibniz Institute for Prevention Research and Epidemiology - BIPS, Bremen, Germany.
Claudia BörnhorstLeibniz Institute for Prevention Research and Epidemiology - BIPS, Bremen, Germany.
Annarita FormisanoInstitute of Food Sciences, Unit of Epidemiology and Population Genetics, National Research Council (ISA-CNR), Avellino, Italy.ORCID http://orcid.org/0000-0001-7328-3716
Toomas VeidebaumNational Institute for Health Development, Tervise Arengu Instituut Tallinn, Tallinn, Estonia.
Michael TornaritisResearch and Education Institute of Child Health, Strovolos, Cyprus.
Stefaan De HenauwDepartment of Public Health/ Department of Movement and Sport Sciences, Faculty of Medicine and Health Sciences, University Gent, Gent, Belgium.
Gabriele EibenSchool of Health Sciences, University of Skövde, Skövde, Sweden.
Monica HunsbergerSchool of Public Health & Community Medicine, Institute of Medicine. The Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden.ORCID http://orcid.org/0000-0003-1779-1286
Dénes MolnárMedical Faculty, Department of Pediatrics, University Pécs, Pécs, Hungary.
Luis A MorenoGENUD (Growth, Exercise, Nutrition and Development) Research Group, Faculty of Health Sciences, Agri-food Institute of Aragón (IA2), University of Zaragoza, Zaragoza, Spain. lmoreno@unizar.es.ORCID http://orcid.org/0000-0003-0454-653X
IDEFICS and I.Family consortia

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo examine the associations between BMI trajectories and changes in fat-free mass index (FFMI) and fat mass index (FMI), assessed via bioelectrical impedance analysis (BIA) and skinfold thickness (ST).

methodsThe study included 4708 European children with BIA data and 3627 with ST data, aged 2-9.9 years at baseline, participating in two waves of the IDEFICS (IDEFICS (Identification and Prevention of Dietary- and Lifestyle-Induced Health Effects in Children and Infants))/I.Family (I. Family (Determinants of eating behavior in European children, adolescents, and their parents)) studies (w0: 2007/08; w2: 2013/14). Children were classified into three BMI trajectory groups: retained normal weight (RNW), remained overweight/obese (ROO), and excessive weight gain (EWG). Analyses of covariance evaluated differences in BMI z-score changes, FFMI, and FMI across groups. Mixed-effects linear regression assessed associations between BMI z-score changes and FFMI/FMI over time.

resultsBMI z-score changes were more strongly associated with FMI (β = 1.16-1.70 in boys; 1.17-1.62 in girls, p < 0.05) than with FFMI, for both BIA and ST. In ROO and EWG groups, associations with FMI were consistently stronger, except among girls <6 years in the ROO group (BIA). In the RNW group, boys >6 years showed stronger associations with FFMI.

conclusionsAssociations between BMI changes and FFMI/FMI vary by BMI trajectory and body composition method. BIA showed closer alignment with BMI changes than ST. These findings suggest that BMI alone may not adequately capture changes in specific body compartments. While convenient, BMI should be interpreted with caution, especially when fat or fat-free mass plays a differential role in disease risk or health outcomes.

Indexed as

Body CompositionBody Mass IndexAdiposityChildChild, PreschoolCohort StudiesElectric ImpedanceEuropeEuropean PeopleFemaleHumansLongitudinal StudiesMaleOverweightSkinfold ThicknessWeight Gain

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.