Evidence map›Paper›PMID 41857300›Full record

ArticleNPJ digital medicine2026

Advancing diagnostic equity through artificial intelligence chest radiograph screening for osteoporosis in Asian populations.

Shu-Han Chen, Ray-E Chang, Chia-En Lien, Dun-Jhu Yang, Pei Yao, Meng-Lu Wu, Kun-Hui Chen

Abstract read
In one paragraph

Article in NPJ digital medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Shu-Han ChenDepartment of Family Medicine, St. Paul's Hospital, Taoyuan, Taiwan.
Ray-E ChangInstitute of Health Policy and Management, College of Public Health, National Taiwan University, Taipei, Taiwan. rchang@ntu.edu.tw.
Chia-En LienAcer Medical Inc., New Taipei City, Taiwan.
Dun-Jhu YangAcer Inc., Taipei City, Taiwan.
Pei YaoInformation Technology Department, St. Paul's Hospital, Taoyuan, Taiwan.
Meng-Lu WuInformation Technology Department, St. Paul's Hospital, Taoyuan, Taiwan.
Kun-Hui ChenDepartment of Orthopedic Surgery, Taichung Veterans General Hospital, Taichung, Taiwan. orthochen@gmail.com.

Funding

Acer Medical Inc N/ASt. Paul's Hospital SPMRP-U1-8002
6 · The paper itself

Abstract

Early identification of abnormal bone mineral density (BMD) through opportunistic screening is critical for preventing osteoporotic fractures. We validated an AI model in 2384 asymptomatic adults (57.7% female; mean age 43.6 years) undergoing health examinations in Taiwan. Using DXA as the reference, the model identified 255 suspected abnormal BMD cases, with 94 (3.9%) DXA-confirmed positive. Population-level performance was robust, yielding an AUC of 0.95 (95% CI 0.93-0.99) and sensitivity of 79.7% (95% CI 71.3-86.5%). Although BMI distributions paralleled East Asian regional trends, intersectional subgroup analyses remain exploratory due to small event counts. Decision curve analysis indicated superior net benefit for AI-based referral over "refer all" or "refer none" strategies, particularly for women with normal BMI (18.5-23 kg/m²). This AI tool offers precise triage for Asian health examination populations, though further validation in multi-center cohorts is required to confirm broad generalizability.

Identifiers

PMID41857300
PMCPMC13153408

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.