Evidence map›Paper›PMID 41857128›Full record

ArticleScientific reports2026

Synthesis, characterization, and biological activities of two new pyrazole Schiff base derivatives.

Suzan Matar, Abdel-Aziz Abu-Yamin, Deeb Taher, Ibrahim A M Saraerah, Mahmoud Salman, Sultan A Saghir, Fatima Ahmad, Sajeda Matar, Lina Buqa'en, Ali Elrashidi

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Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Suzan MatarDepartment of Clinical Laboratory Sciences, School of Science, The University of Jordan, Amman, Jordan. s.mattar@ju.edu.jo.
Abdel-Aziz Abu-YaminDepartment of Chemistry, Faculty of Science, Al-Hussein Bin Talal University, Ma'an, Jordan.
Deeb TaherDepartment of Chemistry, School of Science, The University of Jordan, Amman, Jordan.
Ibrahim A M SaraerahDepartment of Chemistry, Faculty of Science, Al-Hussein Bin Talal University, Ma'an, Jordan.
Mahmoud SalmanDepartment of Chemistry, Faculty of Science, Al-Hussein Bin Talal University, Ma'an, Jordan.
Sultan A SaghirDepartment of Medical Analysis, Faculty of Allied Medical Sciences, Al-Hussein Bin Talal University, Ma'an, Jordan.
Fatima AhmadDepartment of Clinical Laboratory Sciences, School of Science, The University of Jordan, Amman, Jordan.
Sajeda MatarFaculty of Pharmacy, The University of Jordan, Amman, Jordan.
Lina Buqa'enMedical Laboratory Sciences Department, Faculty of Allied Medical Sciences, Al-Ahliyya Amman University, Amman, Jordan.
Ali ElrashidiElectrical Engineering, College of Engineering, University of Business and Technology, Jeddah, Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The development of new heterocyclic scaffolds remains a priority in medicinal chemistry due to the rising challenges of microbial resistance and cancer. In this study, we explored the synergistic potential of combing thiophene-substituted pyrazoles with phenolic Schiff bases. We synthesized two novel derivatives, 3a and 3b, via the condensation of 5-Amino-3-(2-thienyl) pyrazole with salicylaldehyde and 5- bromo-2-hydroxybenzaldehyde. These structures were confirmed using FTIR,

Indexed as

Anti-Bacterial AgentsAntineoplastic AgentsPyrazolesAntifungal AgentsCell Line, TumorHumansMicrobial Sensitivity TestsSchiff BasesStaphylococcus aureusAnti-Bacterial AgentsAntifungal AgentsAntineoplastic AgentsPyrazolesSchiff BasesAnticancerAntimicrobialCharacterizationHemolysisMutagenicityPharmacological activitySchiff base derivativesSynthesis

Identifiers

PMID41857128
PMCPMC13139591

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.