Evidence map›Paper›PMID 41857087›Full record

ArticleScientific data2026

Growth dynamics of 3,909 Escherichia coli single-gene knockouts in rich and minimal media.

Zehui Lao, Bei-Wen Ying

Abstract read
In one paragraph

Article in Scientific data, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Zehui LaoGraduate School of Life and Environmental Sciences, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, 305-8572, Ibaraki, Japan.
Bei-Wen YingGraduate School of Life and Environmental Sciences, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, 305-8572, Ibaraki, Japan. ying.beiwen.gf@u.tsukuba.ac.jp.

Funding

Japan Science and Technology Agency SPRING, JPMJSP2124Japan Society for the Promotion of Science 25K02259
6 · The paper itself

Abstract

High-throughput phenotyping of microbial growth is crucial for understanding genotype-phenotype relationships in systems biology. Linking genetic variation to dynamic growth responses across environments remains challenging. Here, we present a time series dataset representing the growth curves of 3,909 single-gene knockout Escherichia coli strains grown in rich (LB) and minimal (M63) media. Using microplate assays with biological triplicates at 37 °C, we generated 23,454 OD

Indexed as

Escherichia coliCulture MediaDatasets as TopicGene Knockout TechniquesPhenotypeCulture Media

Identifiers

PMID41857087
PMCPMC13153163

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.