Evidence map›Paper›PMID 41857057›Full record

ArticleNature communications2026

CXCR5

Yutiantian Lei, Rui Jia, Chen Chen, Peihai Cao, Jiahong Shi, Mengdi Huang, Qiuyu Mu, Yixin Wang, Dairu Hou, Mingjun Si and 25 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nature communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

35 authors.

Yutiantian Lei *Department of Radiation Oncology, First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China.ORCID http://orcid.org/0000-0001-8357-6790
Rui Jia *Department of Radiation Oncology, First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China.ORCID http://orcid.org/0009-0008-6834-3612
Chen Chen *Department of Pathogenic Microbiology and Immunology, School of Basic Medical Sciences, Xi'an Jiaotong University, Xi'an, Shaanxi, China.
Peihai CaoDepartment of Pathogenic Microbiology and Immunology, School of Basic Medical Sciences, Xi'an Jiaotong University, Xi'an, Shaanxi, China.
Jiahong ShiDepartment of Pathogenic Microbiology and Immunology, School of Basic Medical Sciences, Xi'an Jiaotong University, Xi'an, Shaanxi, China.
Mengdi HuangDepartment of Pathogenic Microbiology and Immunology, School of Basic Medical Sciences, Xi'an Jiaotong University, Xi'an, Shaanxi, China.ORCID http://orcid.org/0009-0007-6887-3659
Qiuyu MuDepartment of Pathogenic Microbiology and Immunology, School of Basic Medical Sciences, Xi'an Jiaotong University, Xi'an, Shaanxi, China.
Yixin WangDepartment of Radiation Oncology, First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China.
Dairu HouDepartment of Pathogenic Microbiology and Immunology, School of Basic Medical Sciences, Xi'an Jiaotong University, Xi'an, Shaanxi, China.
Mingjun SiDepartment of Pathogenic Microbiology and Immunology, School of Basic Medical Sciences, Xi'an Jiaotong University, Xi'an, Shaanxi, China.ORCID http://orcid.org/0009-0006-6382-3815
Ruishan GuoDepartment of Radiation Oncology, First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China.
Jiahao SunDepartment of Radiation Oncology, First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China.ORCID http://orcid.org/0009-0009-1821-4086
Dingge JiangDepartment of Pathogenic Microbiology and Immunology, School of Basic Medical Sciences, Xi'an Jiaotong University, Xi'an, Shaanxi, China.
Yihan WangDepartment of Radiation Oncology, First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China.
Tingting LvDepartment of Pathology, School of Basic Medical Sciences, Xi'an Jiaotong University, Xi'an, Shaanxi, China.
Ruiying WangDepartment of Pathogenic Microbiology and Immunology, School of Basic Medical Sciences, Xi'an Jiaotong University, Xi'an, Shaanxi, China.
Junyi ZhangDepartment of Radiation Oncology, First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China.
Du YangDepartment of Radiation Oncology, First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China.
Hanmin TangDepartment of Radiation Oncology, First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China.
Jianan LiDepartment of Radiation Oncology, First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China.
Liuyi YangDaily-surgery center, First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China.
Renyi DingDepartment of Pathogenic Microbiology and Immunology, School of Basic Medical Sciences, Xi'an Jiaotong University, Xi'an, Shaanxi, China.
Wenhua LiDepartment of Pathogenic Microbiology and Immunology, School of Basic Medical Sciences, Xi'an Jiaotong University, Xi'an, Shaanxi, China.
Haiyan LiuDepartment of Pathogenic Microbiology and Immunology, School of Basic Medical Sciences, Xi'an Jiaotong University, Xi'an, Shaanxi, China.
Anjun JiaoDepartment of Pathogenic Microbiology and Immunology, School of Basic Medical Sciences, Xi'an Jiaotong University, Xi'an, Shaanxi, China.
Lingyun HuiDepartment of Laboratory Medicine, First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China.
Yanxia SuiDepartment of pathology, First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China.
Shan HuangDepartment of Radiation Oncology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'An, China.
Mengjiao CaiDepartment of Radiation Oncology, First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China.
Chenchen HeDepartment of Radiation Oncology, First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China.
Chen LinDepartment of General Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, China.
Fei WangDepartment of Radiation Oncology, First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China.
Jinlu MaDepartment of Radiation Oncology, First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China. majinlu@xjtufh.edu.cn.
Suxia HanDepartment of Radiation Oncology, First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China. shan87@xjtu.edu.cn.ORCID http://orcid.org/0000-0003-0842-3908
Yuzhu HouDepartment of Pathogenic Microbiology and Immunology, School of Basic Medical Sciences, Xi'an Jiaotong University, Xi'an, Shaanxi, China. houyuzhu@xjtu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A substantial portion of patients experience radioresistance, which impedes clinical benefit. The radiation-induced 'protumor' immune response is previously demonstrated to limit antitumor efficacy. However, the detailed mechanism remains to be explored. In this study, we observe CXCR5

Indexed as

MonocytesNeoplasmsReceptors, CXCR5AnimalsB7-H1 AntigenCD8-Positive T-LymphocytesCell Line, TumorCell MovementChemokine CXCL13FemaleGranulocyte-Macrophage Colony-Stimulating FactorHumansHypoxia-Inducible Factor 1, alpha SubunitMacrophagesMiceMice, Inbred C57BLB7-H1 AntigenCD274 protein, humanChemokine CXCL13CXCL13 protein, humanCXCR5 protein, humanGranulocyte-Macrophage Colony-Stimulating FactorHIF1A protein, humanHypoxia-Inducible Factor 1, alpha SubunitPhosphatidylinositol 3-KinasesProgrammed Cell Death 1 ReceptorReceptors, CXCR5TOR Serine-Threonine KinasesVascular Endothelial Growth Factor A

Identifiers

PMID41857057
PMCPMC13168305

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.