Evidence map›Paper›PMID 41857025›Full record

ArticleNature communications2026

Cross-ketone deacylative coupling via oxidative S

Jian-Xiong Yang, Meng-Yao Zhang, Qi Wen, Jia-Run Wang, Yan Zhang, Heng Jiang

Abstract read
In one paragraph

Article in Nature communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jian-Xiong YangShanghai Frontiers Science Center of Drug Target Identification and Delivery, National Key Laboratory of Innovative Immunotherapy, Shanghai Key Laboratory for Molecular Engineering of Chiral Drugs, School of Pharmaceutical Sciences, Shanghai Jiao Tong University, Shanghai, PR China.
Meng-Yao ZhangShanghai Frontiers Science Center of Drug Target Identification and Delivery, National Key Laboratory of Innovative Immunotherapy, Shanghai Key Laboratory for Molecular Engineering of Chiral Drugs, School of Pharmaceutical Sciences, Shanghai Jiao Tong University, Shanghai, PR China.
Qi WenShanghai Frontiers Science Center of Drug Target Identification and Delivery, National Key Laboratory of Innovative Immunotherapy, Shanghai Key Laboratory for Molecular Engineering of Chiral Drugs, School of Pharmaceutical Sciences, Shanghai Jiao Tong University, Shanghai, PR China.
Jia-Run WangShanghai Frontiers Science Center of Drug Target Identification and Delivery, National Key Laboratory of Innovative Immunotherapy, Shanghai Key Laboratory for Molecular Engineering of Chiral Drugs, School of Pharmaceutical Sciences, Shanghai Jiao Tong University, Shanghai, PR China.
Yan ZhangState Key Laboratory of Analytical Chemistry for Life Sciences, School of Chemistry, Chemistry and Biomedicine Innovation Center (ChemBIC), Nanjing University, Nanjing, PR China. njuzy@nju.edu.cn.ORCID http://orcid.org/0000-0002-8858-8894
Heng JiangShanghai Frontiers Science Center of Drug Target Identification and Delivery, National Key Laboratory of Innovative Immunotherapy, Shanghai Key Laboratory for Molecular Engineering of Chiral Drugs, School of Pharmaceutical Sciences, Shanghai Jiao Tong University, Shanghai, PR China. jiangheng@sjtu.edu.cn.ORCID http://orcid.org/0009-0009-1297-8106

Funding

National Natural Science Foundation of China (National Science Foundation of China) 22101176National Natural Science Foundation of China (National Science Foundation of China) 22137003National Natural Science Foundation of China (National Science Foundation of China) 22225703National Natural Science Foundation of China (National Science Foundation of China) 22571197
6 · The paper itself

Abstract

The α-C-C cleavage coupling of ketones offers a highly challenging yet promising approach for C-C bond formation, particularly given the ubiquity and ready accessibility of ketones as fundamental synthons in organic synthesis. However, the deacylative cross-coupling between two distinct ketones via a single activation mode remains an unmet challenge, although this coupling paradigm could be leveraged to construct C(sp

Identifiers

PMID41857025
PMCPMC13168298

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.