Evidence map›Paper›PMID 41856949›Full record

ArticleMagnetic resonance in medicine2026

Deep-Learning-Based Image Reconstruction to Improve End-Diastolic and Systolic Cardiac T1 Mapping.

Daniel Amsel, Jens Wetzl, Daniel Giese, Christoph Tillmanns, Rolf Gebker, Kelvin Chow, Michaela Schmidt, Andreas Lingg, Jens Kübler, Patrick Krumm and 1 more

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Article in Magnetic resonance in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

11 authors.

Daniel AmselMedical Image and Data Analysis (MIDAS.lab), Department of Diagnostic and Interventional Radiology, University of Tuebingen, Tuebingen, Germany.ORCID https://orcid.org/0009-0007-3440-220X
Jens WetzlResearch & Clinical Translation, Magnetic Resonance, Siemens Healthineers AG, Erlangen, Germany.
Daniel GieseResearch & Clinical Translation, Magnetic Resonance, Siemens Healthineers AG, Erlangen, Germany.
Christoph TillmannsDiagnostikum, Berlin, Germany.
Rolf GebkerDiagnostikum, Berlin, Germany.
Kelvin ChowCardiovascular MR R&D, Siemens Healthcare Ltd, Calgary, Canada.ORCID https://orcid.org/0000-0003-0698-1746
Michaela SchmidtResearch & Clinical Translation, Magnetic Resonance, Siemens Healthineers AG, Erlangen, Germany.
Andreas LinggDepartment of Radiology, University Hospital Tuebingen, Tuebingen, Germany.
Jens KüblerDepartment of Radiology, University Hospital Tuebingen, Tuebingen, Germany.
Patrick KrummDepartment of Radiology, University Hospital Tuebingen, Tuebingen, Germany.
Thomas KüstnerMedical Image and Data Analysis (MIDAS.lab), Department of Diagnostic and Interventional Radiology, University of Tuebingen, Tuebingen, Germany.ORCID https://orcid.org/0000-0002-0353-4898

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo develop an image reconstruction method that enables increased spatial resolution cardiac T1 mapping in both the end-diastolic and systolic phase, that shows high T1 agreement with the clinical standard. The resolution gain is achieved by increasing the acceleration rate of MOLLI single-shot images to R = 4, while maintaining a sufficiently short acquisition window.

methodsA modified end-to-end variational network (MappingVN) is proposed. The modifications include a re-ordered sheared-grid sampling pattern, 2D + contrast convolutions and the use of patchwise squeeze-and-excitation layers. The method was evaluated in terms of image quality and T1 agreement with reference MOLLI T1 maps using retrospectively undersampled patient data. Furthermore, the method was additionally evaluated in a prospective setting comparing high-resolution T1 maps (1.14 × 1.14 mm

resultsThe MappingVN showed improved SSIM scores of 0.95 and 0.98 on 1.5T and 3 T compared to 0.93 and 0.96 for GRAPPA. In high-resolution end-diastolic T1 maps stronger T1 agreement (MappingVN: -3 ± 69 ms on 1.5T, -11 ± 70 ms on 3T, GRPPA: -9 ± 129 ms on 1.5T, 14 ± 106 ms) could be observed. For systolic T1 mapping the MappingVN reduced the occurrence of motion artifacts.

conclusionThe proposed method enables high spatial resolution cardiac T1 mapping in both end-diastolic and systolic phases. Resulting maps show good T1 agreement with the clinical standard and may improve the visibility of small focal lesions while reducing partial volume effects.

Indexed as

Deep LearningHeartImage Processing, Computer-AssistedMagnetic Resonance ImagingAlgorithmsDiastoleHumansImage Interpretation, Computer-AssistedProspective StudiesRetrospective StudiesSystoledeep learning reconstructionmyocardial T1 mappingquantitative MRI

Identifiers

PMID41856949
PMCPMC13269227

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