Evidence map›Paper›PMID 41856945›Full record

ArticleMagnetic resonance in medicine2026

Effect of Water Suppression and Metabolite Cycling on Quantification of

Dinesh K Deelchand, Pierre-Gilles Henry

Abstract read
In one paragraph

Article in Magnetic resonance in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Dinesh K DeelchandCenter for Magnetic Resonance Research and Department of Radiology, University of Minnesota, Minneapolis, Minnesota, USA.ORCID 0000-0003-4266-4780
Pierre-Gilles HenryCenter for Magnetic Resonance Research and Department of Radiology, University of Minnesota, Minneapolis, Minnesota, USA.

Funding

TRD4 - Ultrahigh Field Engineering and SafetyP41EB027061 · NIBIB · UNIVERSITY OF MINNESOTA · PI Gregory John Metzger · 2019 to 2026
$11.7M
Institutional Center Cores for Advanced NeuroimagingP30NS076408 · NINDS · UNIVERSITY OF MINNESOTA · PI UGURBIL, KAMIL · 2012 to 2020
$4.2M
Fully Automated Motion-corrected MR Spectroscopy in Human Brain and Spinal CordR01EB030000 · NIBIB · UNIVERSITY OF MINNESOTA · PI DEELCHAND, DINESH KUMAR · 2020 to 2024
$1.3M
NIBIB NIH HHS R01 EB030000NIH HHS 1S10OD017974-01NIH HHS P30 NS076408NIH HHS P41 EB027061NIH HHS R01 EB030000
6 · The paper itself

Abstract

purposeThis study investigates the effect of VAPOR water suppression and metabolite cycling on metabolite quantification and macromolecules in proton magnetic resonance spectroscopy.

methodsSingle-voxel semi-LASER spectra (T

resultsRegion specific differences in macromolecule resonances were observed and the concentration of most metabolites was significantly higher when using MC compared to VAPOR. The difference was most pronounced for total creatine (-14% with VAPOR vs. MC, p < 0.05).

conclusionThe macromolecules spectrum included in the LCModel basis set must be measured with the same water suppression scheme as the metabolite spectrum for accurate quantification.

Indexed as

BrainProton Magnetic Resonance SpectroscopyWaterAdultFemaleHumansMaleReproducibility of ResultsSensitivity and SpecificityWaterbrainmetabolite cyclingsemi‐LASERVAPOR

Identifiers

PMID41856945
PMCPMC13269189

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.