ArticleToxicon : official journal of the International Society on Toxinology2026
Adsorption and detoxification of ochratoxin A using hydrophobic bentonite clay.
Article in Toxicon : official journal of the International Society on Toxinology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
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2 authors.
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Abstract
Mycotoxins such as ochratoxin A (OTA) are hazardous chemicals produced from fungi that frequently contaminate feed ingredients, and this contamination can result in significant economic loss, disease and death. Given the persistent nature of OTA, this study was designed to provide effective and potentially scalable strategies to mitigate acute OTA toxicity using organoclay. The study explores the adsorption behavior of OTA on active binding surfaces of four organoclay composites that were synthesized by modifying sodium bentonite clay surfaces with different amounts of a hydrophobic quaternary ammonium compound (QAC). This modification serves to immobilize and stabilize the QAC. The study evaluates key thermodynamics, kinetics and binding markers including the Gibbs free energy (ΔG), adsorption capacity, enthalpy (ΔH), and binding affinity of these clays for OTA. Additionally, the protective role of these organoclays was evaluated using a sensitive ecotoxicology model. At gastric pH (pH 2), the organoclays demonstrated high adsorption capacities for OTA ranging between 0.34 and 0.51 mol kg
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