Evidence map›Paper›PMID 41856287›Full record

ArticleThe Journal of biological chemistry2026

Targeting Nipah virus replication: A fluorescence polarization assay for high-throughput modulators screening against the N

Hugo Bost, Carine Derviaux, Sonia Longhi

Abstract read
In one paragraph

Article in The Journal of biological chemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Hugo BostArchitecture et Fonction des Macromolécules Biologiques (AFMB), UMR 7257 CNRS and Aix-Marseille Université, Marseille Cedex 09, France. Electronic address: hugo.bost@univ-amu.fr.
Carine DerviauxPlateforme HiTS: Criblage & Drug Design, Centre de Recherche en Cancérologie de Marseille (CRCM), Inserm UMR1068, CNRS UMR7258, Aix Marseille Université U105, Institut Paoli-Calmettes, Marseille Cedex 09, France.
Sonia LonghiArchitecture et Fonction des Macromolécules Biologiques (AFMB), UMR 7257 CNRS and Aix-Marseille Université, Marseille Cedex 09, France. Electronic address: sonia.longhi@univ-amu.fr.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nipah virus (NiV) is a biosafety level 4 pathogen for which no licensed antiviral or vaccine is currently available. Given its pandemic potential and the serious threat it poses to human health, there is an urgent need for robust assays enabling the screening of chemical libraries in search of antiviral candidates. Here, we report the development of a high-throughput competitive fluorescence polarization assay designed to screen compound libraries and identify modulators of the NiV N

Indexed as

Antiviral AgentsFluorescence PolarizationHigh-Throughput Screening AssaysNipah VirusThioredoxinsVirus ReplicationHumansProtein BindingSmall Molecule LibrariesAntiviral AgentsSmall Molecule LibrariesThioredoxinsantiviral agentdrug screeninginhibitorprotein–protein interactionviral replication

Identifiers

PMID41856287
PMCPMC13091328

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.