ArticleBiofabrication2026
A toolbox for microvalve-based bioprinting.
Article in Biofabrication, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Advances in 3D Bioprinting for Scaffold-Based and Scaffold-Free Tissue Engineering and Regenerative Medicine.Gels (Basel, Switzerland) · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
Microvalve-based bioprinting (MBB) enables precise deposition of bioinks in the form of droplets through the controlled ejection of nanoliter-scale cylindrical ligaments. Despite its increasing use in tissue biofabrication, standardization criteria for assessing bioink printability remain limited. In this study, we present a quantitative printability toolbox for evaluating various bioinks, including fibrinogen, collagen type I, Matrigel, alginate, agarose and methacrylated gelatin (GelMA), in the context of MBB. We systematically analyzed how rheological properties and the contact angle influence ligament formation and droplet ejection. High-speed imaging captured ligament dynamics such as velocity and volume as well as droplet-substrate interactions. The role of Tween 20 (T20) surfactant was further investigated to reduce interfacial aggregation and improve droplet uniformity. Our results revealed viscosity and concentration thresholds specific to each bioink, enabling the construction of a comprehensive printability map correlating bioink properties with ligament stability and droplet printability. This framework provides a practical guide for bioink optimization in MBB towards reproducible fabrication of complex biological structures for biomedical applications.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.