Evidence map›Paper›PMID 41855387›Full record

ArticleActa paediatrica (Oslo, Norway : 1992)2026

Emotional and Behavioural Problems in Children With Functional Gastrointestinal Disorders.

Sebastian Weber, Anna Geser, Eva Unternaehrer, Margarete Bolten, Corinne Légeret

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Article in Acta paediatrica (Oslo, Norway : 1992), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Sebastian WeberFaculty of Medicine, University of Basel, Basel, Switzerland.ORCID https://orcid.org/0009-0001-2055-8760
Anna GeserFaculty of Medicine, University of Basel, Basel, Switzerland.
Eva UnternaehrerChild and Adolescent Psychiatric Research Department, University Psychiatric Clinics Basel, University of Basel, Basel, Switzerland.ORCID https://orcid.org/0000-0002-3507-1883
Margarete BoltenFaculty of Medicine, University of Basel, Basel, Switzerland.ORCID https://orcid.org/0000-0001-9273-5845
Corinne LégeretFaculty of Medicine, University of Basel, Basel, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimFunctional gastrointestinal disorders (FGIDs) are common in childhood, but psychological correlates remain poorly understood. We compared emotional and behavioural functioning in children with FGIDs with somatic and healthy controls.

methodsParents of children aged 2-12 years were recruited at the University Children's Hospital Basel (February 2024-February 2025). Children meeting Rome IV criteria formed the Functional Group; those with somatic gastrointestinal diseases and healthy peers served as Somatic and Healthy Controls. Parents completed the Strengths and Difficulties Questionnaire (SDQ) and Patient Health Questionnaire (PHQ-4). Group differences were tested using non-parametric models and adjusted negative binomial regression.

resultsData from 218 children were analysed (Functional n = 66, Somatic n = 62, Healthy n = 90). SDQ total difficulties were markedly higher in FGIDs than in both control groups (p < 0.001). Differences were most pronounced for emotional and hyperactivity problems. Using age-adjusted SDQ total difficulties cut-offs, elevated scores occurred in 45.5% of children with FGIDs, compared with 8.1% in somatic and 10.0% in healthy peers. Parental psychological distress and separation predicted higher difficulties.

conclusionEmotional and behavioural difficulties in FGIDs exceed those observed in somatic gastrointestinal diseases, indicating a particularly high psychosocial burden. These findings highlight the relevance of psychological aspects within integrated paediatric gastroenterology care.

Indexed as

Affective SymptomsChild Behavior DisordersGastrointestinal DiseasesProblem BehaviorCase-Control StudiesChildChild, PreschoolFemaleHumansMaleSurveys and Questionnaireschild mental healthdisorders of gut–brain interactionemotional and behavioural problemsfunctional gastrointestinal disorderspsychosocial factors

Identifiers

PMID41855387
PMCPMC13250960

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.