Evidence map›Paper›PMID 41855331›Full record

ArticleScience (New York, N.Y.)2026

Host-derived nitrate fuels indole production by

Jee-Yon Lee, Scott P Mahan, Thaynara Parente de Carvalho, Henry Nguyen, Chonikarn Singai, Lizbeth Camacho, Mert Tekeli, Yu-Jin Kwon, Ji-Won Lee, Renato L Santos and 3 more

Abstract read
In one paragraph

Article in Science (New York, N.Y.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Gut microbes · 2026
    Trial
  2. Review
  3. Gut microbiota in health and disease.Molecular biomedicine · 2026
    Review
  4. Review
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Jee-Yon LeeDepartment of Medical Microbiology and Immunology, School of Medicine, University of California at Davis, Davis, CA, USA.ORCID 0000-0002-6376-2681
Scott P MahanDepartment of Medical Microbiology and Immunology, School of Medicine, University of California at Davis, Davis, CA, USA.
Thaynara Parente de CarvalhoDepartment of Medical Microbiology and Immunology, School of Medicine, University of California at Davis, Davis, CA, USA.ORCID 0000-0002-7158-8249
Henry NguyenDepartment of Medical Microbiology and Immunology, School of Medicine, University of California at Davis, Davis, CA, USA.ORCID 0000-0002-6737-1485
Chonikarn SingaiDepartment of Medical Microbiology and Immunology, School of Medicine, University of California at Davis, Davis, CA, USA.ORCID 0009-0008-8274-659X
Lizbeth CamachoDepartment of Medical Microbiology and Immunology, School of Medicine, University of California at Davis, Davis, CA, USA.ORCID 0000-0003-3826-9630
Mert TekeliDepartment of Medical Microbiology and Immunology, School of Medicine, University of California at Davis, Davis, CA, USA.ORCID 0009-0008-0659-722X
Yu-Jin KwonDepartment of Family Medicine, Yongin Severance Hospital, Yonsei University College of Medicine, Yongin, Republic of Korea.ORCID 0000-0002-9021-3856
Ji-Won LeeDepartment of Family Medicine, Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea.ORCID 0000-0002-2666-4249
Renato L SantosDepartamento de Clínica e Cirurgia Veterinárias, Escola de Veterinária, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil.ORCID 0000-0002-4830-0470
Renée M TsolisDepartment of Medical Microbiology and Immunology, School of Medicine, University of California at Davis, Davis, CA, USA.ORCID 0000-0001-9131-6657
Sebastian E WinterDepartment of Medical Microbiology and Immunology, School of Medicine, University of California at Davis, Davis, CA, USA.ORCID 0000-0003-1532-9178
Andreas J BäumlerDepartment of Medical Microbiology and Immunology, School of Medicine, University of California at Davis, Davis, CA, USA.ORCID 0000-0001-9152-7809

Funding

Mechanism of Colonization ResistanceR01AI112949 · NIAID · UNIVERSITY OF CALIFORNIA AT DAVIS · PI Andreas J Baumler · 2016 to 2026
$5.2M
Interspecies microbial interactions in CKDR01DK138912 · NIDDK · UNIVERSITY OF CALIFORNIA AT DAVIS · PI Andreas J Baumler, Sebastian E Winter · 2024 to 2026
$2.1M
NIAID NIH HHS R01 AI112949NIDDK NIH HHS R01 DK138912
6 · The paper itself

Abstract

Chronic kidney disease (CKD) is linked to an elevated fecal abundance of

Indexed as

Escherichia coliIndicanIndolesNitratesRenal Insufficiency, ChronicAnimalsDisease ProgressionFecesGastrointestinal MicrobiomeHumansKidneyMaleMiceMice, Inbred C57BLNitric Oxide Synthase Type IIIndicanindoleIndolesNitratesNitric Oxide Synthase Type IINos2 protein, mouse

Identifiers

PMID41855331
PMCPMC13004173

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.