ArticleActa paediatrica (Oslo, Norway : 1992)2026
Early Diagnoses of Concern Appear Valid in Predicting Adverse Neurodevelopmental Outcomes in Mid-Childhood.
Article in Acta paediatrica (Oslo, Norway : 1992), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo examine the relationship between 'diagnoses of neurodevelopmental concern' before the age of 2 years and definite adverse outcomes before age 10.
methodData from national registries were linked. Children born in Denmark from 1994 to 2017 were included. Eight diagnoses of neurodevelopmental concern recorded before age 2 were compared to four definite outcomes recorded before age 10. The association was also analysed in three subpopulations at risk of perinatal brain damage.
resultsA total of 1.5 million children were included. At least one diagnosis of neurodevelopmental concern was recorded in 34 392 (2.3%) of children before the age of 2 years, but numbers increased over the years. Definite outcomes were recorded in 35 300 (2.3%) children before age 10. Of these 7 757 (22.6%) had previously had an early diagnosis of neurodevelopmental concern OR (95% CI) = 12.0 (11.5; 12.5). In the three subpopulations, diagnoses of concern as well as the risk of a definite outcome were increased 3-to-4 fold.
conclusionEarly diagnosis of concern appeared valid indicators of adverse neurodevelopmental outcome. The use of diagnoses of concern increased gradually over the years and cannot serve as a simple monitor at the population level.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.