Evidence map›Paper›PMID 41855118›Full record

ArticlePloS one2026

Orthostatic tolerance and training methodology in physically active men and women.

Hayden W Hess, Courtney E Wheelock, David Hostler

Abstract read
In one paragraph

Article in PloS one, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Hayden W HessCenter for Research and Education in Special Environments (CRESE), Department of Exercise and Nutrition Sciences, University at Buffalo, Buffalo, New York, United States of America.ORCID https://orcid.org/0000-0002-8432-7208
Courtney E WheelockCenter for Research and Education in Special Environments (CRESE), Department of Exercise and Nutrition Sciences, University at Buffalo, Buffalo, New York, United States of America.
David HostlerCenter for Research and Education in Special Environments (CRESE), Department of Exercise and Nutrition Sciences, University at Buffalo, Buffalo, New York, United States of America.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Previous studies suggest that training methodology alters orthostatic tolerance in elite and/or well-trained athletes. However, little is known about the effect of training methodology on orthostatic tolerance among the general physically active population. We tested the hypothesis that men and women participating in hybrid training (i.e., combined resistance and endurance training) would demonstrate superior orthostatic tolerance compared to aerobic endurance trained and recreationally active individuals. Twenty-nine participants were classified into one of the three groups depending on their current, self-reported training methodology. All participants reported at least 150 minutes per week of recreational activity (Recreationally Active Group; n = 10), hybrid training classes (Hybrid Group; n = 9), or endurance training (Endurance Group; n = 10) for ≥6 months. Anthropometrics (height and mass) were measured, and body composition was assessed via air displacement plethysmography. Orthostatic tolerance was assessed by a progressive lower-body negative pressure (LBNP) test and quantified via cumulative stress index (CSI). CSI did not differ between groups (p = 0.2542). Fat-free mass (FFM) was positively related to CSI (R² = 0.4092) and differed between groups (recreationally active: 56.1 ± 10.0 kg; hybrid: 65.5 ± 13.2 kg; endurance: 51.2 ± 10.5 kg; p = 0.0453). However, CSI normalized to FFM did not differ between groups (p = 0.6210; FFM missing for two participants). Among recreationally active adults, training methodology does not appear to modify orthostatic tolerance. Consistent with previous work, we report that body composition and anthropometrics are related to orthostatic tolerance highlighting the importance in maintaining lean mass regardless of training methodology.

Indexed as

Endurance TrainingExerciseOrthostatic IntoleranceAdultBody CompositionFemaleHumansLower Body Negative PressureMalePhysical EnduranceResistance TrainingYoung Adult

Identifiers

PMID41855118
PMCPMC13001907

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.