Evidence map›Paper›PMID 41855003›Full record

ReviewTissue engineering and regenerative medicine2026

Recent Progress of Dopamine-Modified Tissue Adhesives for Biomedical Applications in Underwater Environments.

Chong-Su Cho, Gi-Yeon Han, Eun Byul Koh, Yo-Han Kim, Yeon Ho Je, Hyun-Joong Kim

Abstract readReview
In one paragraph

Review in Tissue engineering and regenerative medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Chong-Su Cho *Department of Agricultural Biotechnology, Research Institute of Agriculture and Life Sciences, Seoul National University, Seoul, 08826, Republic of Korea.
Gi-Yeon HanDepartment of Chemical Engineering, Chung-Ang University, Seoul, 06974, Republic of Korea.
Eun Byul KohDepartment of Agricultural Biotechnology, Research Institute of Agriculture and Life Sciences, Seoul National University, Seoul, 08826, Republic of Korea.
Yo-Han KimDepartment of Agricultural Biotechnology, Research Institute of Agriculture and Life Sciences, Seoul National University, Seoul, 08826, Republic of Korea.
Yeon Ho JeDepartment of Agricultural Biotechnology, Research Institute of Agriculture and Life Sciences, Seoul National University, Seoul, 08826, Republic of Korea. btrus@snu.ac.kr.
Hyun-Joong KimProgram in Environmental Materials Science, Department of Agriculture, Forestry and Bioresources, Seoul National University, Seoul, 08826, Republic of Korea. hjokim@snu.ac.kr.ORCID http://orcid.org/0000-0002-3897-7939

Funding

National Research Foundation of Korea NRF2020R111A1A01053275Rural Development Administration PJ01497803
6 · The paper itself

Abstract

backgroundUnderwater adhesion of polymeric adhesives is highly desirable in specific applications such as wound dressings, wearable devices, bioelectronic devices, biosensors, and water pipeline leakage repairing. However, underwater bonding is considerably different from bonding in air because interfacial water molecules substantially weaken the intimate contact adhesion between the adhesive and submerged surfaces, thus significantly limiting the application of adhesives in various fields.

methodThis review was compiled by searching relevant references on PubMed database (before April 2025) based on selected keywords.

resultsRecently, many wet adhesion technologies and diverse and flexible adhesive materials have been employed to address the weak adhesion strengths and inferior mechanical properties in underwater environments. Among several strategies, mussel-inspired catechol-based underwater adhesion has gained the attention of scientists because mussel-inspired tissue adhesives (TAs) demonstrate numerous advantages including many interactions with substrates, various designs of some interesting smart TAs, and excellent adhesion based on several interfacial interactions dominated by 3,4-dihydroxyphenylalanine, a catecholic amino acid in mussel adhesive proteins.

conclusionWe discuss the mechanism of catechol-based underwater adhesion, classification of underwater adhesives, and characteristics, applications, advantages, and disadvantages of dopamine (DA)-modified polymeric TAs. Furthermore, we review stimuli-responsive TAs and the essential factors affecting the adhesions of DA-modified TAs in underwater environments. Finally, we discuss some current technical challenges and future perspectives for underwater adhesion.

Indexed as

DopamineTissue AdhesivesWaterAnimalsBivalviaHumansDopamineTissue AdhesivesWaterBiomedical applicationTissue adhesivesUnderwater environments

Identifiers

PMID41855003
PMCPMC13323430

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.