ArticlePlant cell reports2026
A soybean EIN transcription factor confers resistance to Phytophthora sojae and favorable agronomic traits.
Article in Plant cell reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
15 authors.
Funding
Abstract
key messageThe transcription factor GmPEIN3 enhances resistance to Phytophthora sojae via ethylene-mediated antioxidant regulation and improves favorable agronomic traits in soybean. Phytophthora sojae is a devastating pathogen of soybean, and developing cultivars that combine high yield with strong disease resistance is a primary breeding objective. However, genes that coordinately regulate these two crucial traits have rarely been identified. In a previous study, using a combination of subtractive suppression hybridization (SSH) and cDNA microarray analysis on the highly resistant soybean variety 'Suinong 10', we identified a promising candidate, GmPEIN3 (Glycine max P. sojae-responsive EIN3), an EIN-type transcription factor. In this work, we confirmed that the expression of GmPEIN3 was potently induced by P. sojae infection in resistant soybean germplasm. Overexpression of GmPEIN3 in soybean resulted in enhanced resistance to P. sojae, while RNA-interference (RNAi) silencing led to increased susceptibility. Transcriptome analysis revealed that GmPEIN3 modulates plant hormone signal transduction and phenylpropanoid biosynthesis pathways. Consistently, ethylene (ET) levels, along with the activities and transcript levels of key antioxidant enzymes (SOD, POD, CAT, and GPX), were markedly higher in GmPEIN3-overexpressing (GmPEIN3-OE) transgenic soybean than in wild type (WT). Mechanistically, molecular assays demonstrated that GmPEIN3 directly binds to and transactivates the promoters of the ET biosynthesis gene GmACO3 and antioxidant-related genes GmSODB and GmPOD21, thereby promoting ET production and enhancing antioxidant defense capacity. Moreover, GmPEIN3-OE lines exhibited significant increases in effective pod number, seeds per plant, and 100-seed weight, whereas these traits were markedly reduced in RNAi lines. Taken together, these results suggest that GmPEIN3 plays a positive dual role in soybean, enhancing P. sojae resistance through the modulation of ethylene signaling and antioxidant defense systems, and simultaneously improving yield-related agronomic traits.
Indexed as
Identifiers
41854874What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.