ArticleJapanese journal of radiology2026
Diagnosis of multivessel coronary artery disease using
Article in Japanese journal of radiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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9 authors.
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Abstract
purposeQuantitative MATERIALS AND
methodsAmong patients who underwent
resultsMVD was identified in 51% of patients, while 49% were classified as non-MVD. Global MFR did not differ significantly between the MVD and non-MVD groups (1.44 ± 0.32 vs. 1.53 ± 0.34; p = 0.220). On multivariate analysis, the presence of a perfusion defect with a fill-in pattern on qualitative PET imaging was the only independent predictor of MVD (OR 13.80; p = 0.002). Among non-MVD patients, contributors to reduced global MFR included high resting MBF in 22, insufficient pharmacological stress in 12, influence of body motion artifacts in 12, severe single-vessel disease in 7, and heart failure in 5. Multiple contributing factors were suspected in 19 patients. Five patients were classified as "others," but were suspected of having coronary microvascular dysfunction.
conclusionsIn real-world clinical practice, global MFR can be reduced by multiple factors. Among patients with reduced global MFR, the presence of a perfusion defect with a fill-in pattern on qualitative PET imaging is the strongest indicator of MVD.
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