ArticleOrthopaedic surgery2026
Temporal Changes in Key Hematological and Inflammatory-Immune Markers Among Elderly Patients Following Hip Fracture: A Five-Day Serial Assessment.
Article in Orthopaedic surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
Abstract
objectiveHip fracture is a severe injury in the elderly population and can trigger a strong physiologic stress reaction with potential impact on clinical outcomes. However, few data are available on the temporal evolution of hematologic parameters after this injury. This study aimed to evaluate the temporal trends of key hematological and inflammatory-immune markers in elderly patients with hip fractures.
methodsA retrospective cohort study was conducted among elderly patients with hip fractures managed at a tertiary referral center from January 2022 to October 2024. Included patients were required to have both complete serial hematological measurements obtained during the first 5 days post-fracture and relevant clinical data. We used generalized estimating equation models for repeated measurements to describe the temporal trends of key hematological markers, with analyses stratified by fracture type and age group.
resultsA total of sixty patients were included, with a mean age of 80 ± 7.4 years (range: 65-96 years) and 68.3% females (n = 41). Within the first 1-5 days post-fracture, hemoglobin decreased by a mean of 9.66 g/L, hematocrit by 3.10 percentage points, neutrophil percentage by 8.12 percentage points, neutrophil count by a mean of 2.41 × 10
conclusionsHemoglobin, hematocrit, neutrophil percentage, neutrophil count, and NLR progressively decrease during days 1-5 after hip fracture in older patients, whereas lymphocyte and monocyte counts exhibit biphasic patterns and vary significantly according to fracture type and age. These findings may help clinicians in interpreting early post-fracture laboratory dynamics and provide a basis for future outcome-oriented validation.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.