Evidence map›Paper›PMID 41854632›Full record

ArticleOrthopaedic surgery2026

The Lateral Alignment Angle: A Novel Method for Evaluating Lateral Patellar Tilt With High Accuracy, Good Reproducibility, and Independence From Patellofemoral Joint Morphology.

Li Minghao, Fan Wen, Liu Qiang, Cui Guoqing

Abstract read
In one paragraph

Article in Orthopaedic surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Li MinghaoDepartment of Sports Medicine, Peking University Third Hospital, Institute of Sports Medicine of Peking University, Beijing, China.
Fan WenDepartment of Rehabilitation, Peking University Third Hospital, Beijing, China.
Liu QiangDepartment of Sports Medicine, Peking University Third Hospital, Institute of Sports Medicine of Peking University, Beijing, China.
Cui GuoqingDepartment of Sports Medicine, Peking University Third Hospital, Institute of Sports Medicine of Peking University, Beijing, China.ORCID https://orcid.org/0000-0002-7194-1284

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveExcessive lateral pressure syndrome (ELPS), a major cause of anterior knee pain, stems from axial lateral patellar tilt. Current diagnostic methods exhibit limited accuracy, poor reproducibility, and difficulty in cases with morphological abnormalities. This study introduces the Lateral Alignment Angle (LAA) as a novel measurement technique.

methodsIn this retrospective study (June 2021-March 2025), 150 patients were enrolled and matched 1:1 with controls (total n = 300). Two senior surgeons independently measured LAA, Lateral Patellofemoral Angle (LPFA), Patellar Tilt Angle (PTA), and Patellofemoral Index (PFI) at separate time points. Receiver operating characteristic (ROC) curves were constructed to evaluate diagnostic performance, with area under the curve (AUC) computed and optimal cut-off determined by maximum Youden index. Intraclass correlation coefficients (ICC) assessed interobserver reproducibility.

resultsLAA demonstrated superior diagnostic accuracy with an AUC of 0.913, sensitivity of 89.3%, specificity of 88.0%, and overall accuracy of 88.7%, all significantly outperforming LPFA and PTA. LAA achieved higher positive (88.2%) and negative predictive values (89.2%), with a positive likelihood ratio of 7.44 and negative likelihood ratio of 0.12. The ICC for LAA was 0.782, indicating good interobserver reliability. The optimal diagnostic cut-off value was determined to be 5.35°.

conclusionsThe LAA is a stable, accurate measurement that minimizes morphological influence on patellofemoral joint assessment. An LAA greater than 5.35° reliably indicates lateral patellar tilt, providing enhanced diagnostic utility and improved clinical management of ELPS.

Indexed as

PatellaPatellofemoral JointAdultFemaleHumansMaleMiddle AgedReproducibility of ResultsRetrospective StudiesSensitivity and Specificityaxial radiographexcessive lateral pressure syndromelateral alignment anglepatella

Identifiers

PMID41854632
PMCPMC13056478

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.