ArticleMedical mycology2026
Co-variation between blood stream infections with Candida species versus Pseudomonas aeruginosa, Staphylococcus aureus, and other isolates among 60 ICU patient cohorts.
Article in Medical mycology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Abstract
backgroundStaphylococcus aureus, Pseudomonas aeruginosa, Enterococcal species, Coagulase-negative Staphylococci, Acinetobacter species, and Candida species are common blood stream infection (BSI) isolates among intensive care unit (ICU) cohorts. That Candida species might interact with bacteria at mucosal surfaces to facilitate invasive infections prompts the question as to the degree of co-variance between Candida species versus bacteria among BSI isolates.
objectivesTo estimate the co-variance between Candida species versus each of these five bacteria as BSI isolates among ICU patient cohorts.
methodsThe literature was searched opportunistically for studies reporting ICU patient cohorts listing Candida species among BSI isolates. The associations of the BSI incidence proportion per 100 patients were converted to logits and modelled using ellipse plots.
resultsThe median overall BSI incidence proportion was 7.8% (interquartile range; 4.8%-11.6%). Among 60 cohorts (50 publications), correlation with the incidence proportion of Candidemia was apparent for Acinetobacter species (correlation coefficient = 0.69), Staphylococcus aureus (0.47), and Pseudomonas aeruginosa (0.4) but less so for Coagulase-negative Staphylococci (0.37) and Enterococcal species (0.32).
conclusionsThere are various degrees of co-variance between the BSI incidence proportion amongst the five types of bacteria and Candida species among ICU cohorts.
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