Evidence map›Paper›PMID 41854260›Full record

ArticleJournal of virology2026

Structural and phylogenetic analyses of umbravirus and umbra-like virus genomes suggest evolution of capsid-like proteins from 30K movement proteins.

Anne E Simon, Jason M Needham, Anna Mikkelsen, Osama Atallah

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of virology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Anne E SimonDepartment of Cell Biology and Molecular Genetics, University of Maryland College Park, College Park, Maryland, USA.ORCID 0000-0001-6121-0704
Jason M NeedhamDepartment of Cell Biology and Molecular Genetics, University of Maryland College Park, College Park, Maryland, USA.
Anna MikkelsenDepartment of Cell Biology and Molecular Genetics, University of Maryland College Park, College Park, Maryland, USA.
Osama AtallahDepartment of Cell Biology and Molecular Genetics, University of Maryland College Park, College Park, Maryland, USA.

Funding

National Science Foundation 312990-0001
6 · The paper itself

Abstract

Plant umbraviruses (UVs) encode, in embedded open reading frames, an unstructured movement protein (MP) (ORF3) required for vascular long-distance movement and a structured 30K-type MP (ORF4) for cell-to-cell movement. UVs do not encode capsid proteins and require helper viruses for vector acquisition. Umbra-like viruses (ULVs) comprise two groups whose RNA-dependent RNA polymerases share significant similarity with UVs and whose non-replicase ORFs, if any, are either single, embedded, or separate. Group 2 ULVs, which lack encoded MPs, use a host-encoded MP and do not require a helper virus, presumably due to encoding a capsid-like protein. Group 1 ULVs are more closely related to UVs and have been identified in Ageratum, Arborvitae,

Indexed as

Capsid ProteinsEvolution, MolecularGenome, ViralPhylogenyPlant Viral Movement ProteinsOpen Reading FramesCapsid ProteinsPlant Viral Movement Proteins-1 ribosomal frameshiftingcap-independent translation enhancerISS 3ʹCITEsRNA translation structuresvirus evolutionvirus movement proteins

Identifiers

PMID41854260
PMCPMC13098196

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.