ArticleDeutsches Arzteblatt international2026
Single or Double Embryo Transfer for Infertility: An Evaluation of Registry Data From Over 22 000 Treatment Cycles.
Article in Deutsches Arzteblatt international, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- Vanishing Twin Syndrome After In Vitro Fertilization and Embryo Transfer: Mechanisms, Perinatal Consequences, Diagnostic Pitfalls, and Prevention.Biomedicines · 2026Review
- Fewer Premature Births After Assisted Reproduction.Deutsches Arzteblatt international · 2026Article
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Authors and funding
12 authors.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundSingle embryo transfer (SET) is considered the most effective method for reducing multiple pregnancies in assisted reproduction. Nevertheless, couples in Germany often opt for double embryo transfer (DET) in the hope of achieving a higher success rate. The aim of this study was to evaluate the effectiveness of two consecutive SETs compared to one DET.
methodsWe conducted a retrospective analysis of data from 133 German fertility clinics. Treatment cycles between January 2017 and December 2022 were analyzed. The parameters examined were the clinical pregnancy rate (CPR) and the live birth rate (LBR), the type of birth (single or multiple), the number of children born, the percentage of premature births, and birth weight.
resultsThe rates of clinical pregnancy and live birth after fresh transfer were higher after DET than after SET (49.2% vs. 45.1% and 38.4% vs. 35.2%, respectively), but more women achieved a live birth with two SETs than with one DET (5111 of 11 205 [45.6%] vs. 4304 of 11 205 [38.4%] after DET). The number of children born per 1000 women was higher after DET (503) than after two cycles of SET (464), but DET resulted in significantly more multiple births (30.3% vs. 1.7%), fewer singleton births (26.8% vs. 37.4%), more premature births (46.5% vs. 18.1%), lower birth weight (2924.8 ± 756.8 g vs. 3264.4 ± 487.0), and significantly more very premature births.
conclusionTwo consecutive SETs lower the risks associated with DET with a comparable success rate in terms of the number of babies born.
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