Evidence map›Paper›PMID 41854132›Full record

ArticleMolecular ecology resources2026

Tetraopes Milkweed Beetle Genomes Elucidate the Adaptive Basis of a Temperate Coevolutionary Radiation.

Sangil Kim, Brian D Farrell

Abstract read
In one paragraph

Article in Molecular ecology resources, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Sangil KimMuseum of Comparative Zoology and Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, MA, USA.ORCID https://orcid.org/0000-0003-2758-8943
Brian D FarrellMuseum of Comparative Zoology and Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, MA, USA.ORCID https://orcid.org/0000-0002-6843-0539

Funding

David Rockefeller Center for Latin American Studies, Harvard University : Faculty GrantFaculty of Arts and Sciences, Harvard University: Dean's Competitive Fund for Promising ScholarshipMuseum of Comparative Zoology, Harvard University : Putnam Expedition GrantNational Institute of Biological Resources NIBR202405101National Institute of Biological Resources NIBR202505101National Institute of Biological Resources NIBR202605103National Research Foundation of Korea 2019R1A6A1A10073437
6 · The paper itself

Abstract

The coevolutionary radiation of 27 species of Tetraopes longhorned beetles and their Asclepias milkweed hosts represents a classic example of adaptive evolution driven by plant chemical defences and herbivore counteradaptations. Investigations to date, however, have focused on a single species, Tetraopes tetrophthalmus, which feeds on the moderately toxic Asclepias syriaca, providing limited comparative data for hypothesis testing. Here, we present reference-quality genomes for three Tetraopes species, T. sublaevis, T. tetrophthalmus, and T. melanurus, each largely specialised on an Asclepias host with distinct cardenolide toxicity, to investigate the genomic basis of their adaptations to evolving plant defences. We identify key amino acid substitutions in the Na

Indexed as

Adaptation, BiologicalAsclepiasBiological CoevolutionColeopteraGenome, InsectAnimalsCardenolidesEvolution, MolecularPhylogenySelection, GeneticCardenolidescardenolide resistancechromosome‐scale genome assemblyinsect–plant coevolutionmuseomicsPCWDE

Identifiers

PMID41854132
PMCPMC13001012

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.