Evidence map›Paper›PMID 41854091›Full record

ArticlePlant, cell & environment2026

BrCCX1 Negatively Regulates Calcium-Mediated Clubroot Resistance in Chinese Cabbage.

Jing Zhang, Xinlei Wang, Sheng Chen, Wenjie Ge, Bo Zhang, Nan Wang, Ruiqin Ji

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Plant, cell & environment, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jing ZhangLiaoning Key Laboratory of Genetics and Breeding for Cruciferous Vegetable Crops, College of Horticulture, Shenyang Agricultural University, Shenyang, Liaoning, China.
Xinlei WangLiaoning Key Laboratory of Genetics and Breeding for Cruciferous Vegetable Crops, College of Horticulture, Shenyang Agricultural University, Shenyang, Liaoning, China.
Sheng ChenThe UWA Institute of Agriculture, The University of Western Australia, Perth, WA, Australia.
Wenjie GeLiaoning Key Laboratory of Genetics and Breeding for Cruciferous Vegetable Crops, College of Horticulture, Shenyang Agricultural University, Shenyang, Liaoning, China.
Bo ZhangLiaoning Key Laboratory of Genetics and Breeding for Cruciferous Vegetable Crops, College of Horticulture, Shenyang Agricultural University, Shenyang, Liaoning, China.
Nan WangLiaoning Key Laboratory of Genetics and Breeding for Cruciferous Vegetable Crops, College of Horticulture, Shenyang Agricultural University, Shenyang, Liaoning, China.
Ruiqin JiLiaoning Key Laboratory of Genetics and Breeding for Cruciferous Vegetable Crops, College of Horticulture, Shenyang Agricultural University, Shenyang, Liaoning, China.ORCID https://orcid.org/0000-0003-1934-7197

Funding

the National Natural Science Foundation of China 32102377the National Natural Science Foundation of China 32272717
6 · The paper itself

Abstract

Chinese cabbage (Brassica rapa L. ssp. pekinensis) is severely threatened by clubroot disease caused by Plasmodiophora brassicae. In this study, the expression of Cation/Ca²⁺ exchanger 1 in B. rapa, BrCCX1, was found to be significantly induced by P. brassicae in Chinese cabbage. BrCCX1 was verified as a negative regulator of clubroot resistance in A. thaliana ccx1 mutant, and BrCCX1-silenced/-overexpressed Chinese cabbage. Exogenous calcium induced clubroot resistance in Chinese cabbage, and silencing of BrCCX1 enhanced this resistance. These results suggested that the negative regulation of BrCCX1 to clubroot resistance is related to calcium signal. BrMYB106 was identified as a direct binder and negative regulator of the BrCCX1 promoter through yeast one-hybrid (Y1H), Dual-luciferase (LUC) and β-glucuronidase (GUS) activity assay. BrMYB106 was verified as a positive regulator of clubroot resistance by virus-induced gene silencing (VIGS) and transiently overexpression. In summary, BrCCX1 is a negative regulator of calcium-mediated clubroot resistance modulated by BrMYB106. The study provided the basis for utilising the BrCCX1 gene to develop clubroot-resistant cultivars in Chinese cabbage.

Indexed as

Brassica rapaCalciumDisease ResistancePlant DiseasesPlant ProteinsPlasmodiophoridaArabidopsisGene Expression Regulation, PlantGene SilencingPlant RootsPlants, Genetically ModifiedPromoter Regions, GeneticCalciumPlant ProteinsBrCCX1BrMYB106Chinese cabbageclubroot diseasePlasmodiophora brassicae

Identifiers

PMID41854091
PMCPMC13353733

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.