Evidence map›Paper›PMID 41853834›Full record

SynthesisFrontiers in psychology2026

Effectiveness of psychological interventions for parents of children eligible for paediatric palliative care: a systematic review and meta-analysis.

Yolanda Álvarez-Pérez, Andrea Duarte-Díaz, Amado Rivero-Santana, Alejandra Abrante-Luis, Bernat Carreras, Diego Infante-Ventura, Vanesa Ramos-García, Alezandra Torres-Castaño, Estefanía Herrera-Ramos, Juan Luis Marrero Gómez and 1 more

Abstract readSystematic Review
In one paragraph

Synthesis in Frontiers in psychology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Yolanda Álvarez-PérezCanary Islands Health Research Institute Foundation (FIISC), Tenerife, Spain.
Andrea Duarte-DíazCanary Islands Health Research Institute Foundation (FIISC), Tenerife, Spain.
Amado Rivero-SantanaCanary Islands Health Research Institute Foundation (FIISC), Tenerife, Spain.
Alejandra Abrante-LuisCanary Islands Health Research Institute Foundation (FIISC), Tenerife, Spain.
Bernat CarrerasDepartment of Adult Psychiatry and Psychology, Institute of Neurosciences (ICN), Hospital Clinic, Barcelona, Spain.
Diego Infante-VenturaCanary Islands Health Research Institute Foundation (FIISC), Tenerife, Spain.
Vanesa Ramos-GarcíaCanary Islands Health Research Institute Foundation (FIISC), Tenerife, Spain.
Alezandra Torres-CastañoCanary Islands Health Research Institute Foundation (FIISC), Tenerife, Spain.
Estefanía Herrera-RamosCanary Islands Health Research Institute Foundation (FIISC), Tenerife, Spain.
Juan Luis Marrero GómezPaediatric Palliative Care Unit, Hospital Universitario Virgen del Rocío, Seville, Spain.
Lilisbeth Perestelo-PérezEvaluation Unit (SESCS), Canary Islands Health Service (SCS), Tenerife, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Paediatric palliative care (PPC) is an early, holistic model addressing the physical, psychological, social, and spiritual needs of children with life-limiting or life-threatening conditions and their families. Parents frequently experience high psychological distress, and although psychological support is a core PPC component, empirical evidence on the effectiveness of interventions within this context remains limited, particularly across non-oncological conditions. This systematic review and meta-analysis aimed to evaluate the effectiveness of psychological interventions for parents of children eligible for PPC. Methods: A systematic search of MEDLINE, Embase, CINAHL, APA PsycINFO, and CENTRAL was conducted in July 2024 and updated in Embase in November 2025. Randomized controlled trials evaluating psychological interventions for parents of children under 18 years eligible for PPC were included. Methodological quality was assessed using the Cochrane Risk of Bias tool for randomized trials (RoB 2). The review was conducted in accordance with PRISMA guidelines, and random-effects meta-analyses were performed where appropriate. Results: Thirty-six studies were included. Although the review aimed to capture studies involving parents of children with various life-limiting conditions eligible for PPC, the evidence base was almost exclusively oncology-focused: only one study was conducted within a PPC context, and all studies involved parents of children with cancer. The psychological interventions were heterogeneous and frequently multimodal, with cognitive-behavioural therapy being the most common approach. Meta-analyses showed primarily short-term significant moderate-to-large effect sizes, indicating improvements in anxiety ( Discussion: The findings suggest that psychological interventions, particularly those based on cognitive behavioural approaches, are effective in reducing psychological distress and enhancing positive psychological outcomes in the short term among parents of children with cancer who are eligible for PPC. However, the scarcity of studies explicitly conducted within PPC settings highlights the need for further high-quality trials across a wider range of life-limiting and life-threatening conditions. Systematic review registration: https://www.crd.york.ac.uk/PROSPERO/view/CRD42024594171, CRD42024594171.

Indexed as

cancerfamilieslife-limitinglife-threatening illnesspaediatric populationpalliative careparentpsychological interventions

Identifiers

PMID41853834
PMCPMC12992277

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.