Evidence map›Paper›PMID 41853832›Full record

ArticleFrontiers in psychology2026

Practical judgment in aging: examining behavioral vulnerabilities and neurobiological correlates.

Nicole Sergeyev, Abi Heller-Wight, Caroline Nester Rooney, Nadia Paré, Anjali Krishnan, David G Ellis, Chloe Moffitt, Robert M Roth, David E Warren, Laura Rabin

Abstract read
In one paragraph

Article in Frontiers in psychology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
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0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Nicole Sergeyev *Department of Psychology and Neuroscience, Duke University, Durham, NC, United States.
Abi Heller-Wight *Department of Neurological Sciences, University of Nebraska Medical Center, Omaha, NE, United States.
Caroline Nester RooneyDepartment of Psychology, The Graduate Center of The City University of New York, New York, NY, United States.
Nadia ParéDepartment of Psychiatry, UCONN Health, Farmington, CT, United States.
Anjali KrishnanDepartment of Psychology, Brooklyn College of The City University of New York, Brooklyn, NY, United States.
David G EllisDepartment of Neurosurgery, University of Nebraska Medical Center, Omaha, NE, United States.
Chloe MoffittDepartment of Neurology, Albert Einstein College of Medicine, Bronx, NY, United States.
Robert M RothDepartment of Psychiatry, Dartmouth Geisel School of Medicine, Lebanon, NH, United States.
David E WarrenDepartment of Neurological Sciences, University of Nebraska Medical Center, Omaha, NE, United States.
Laura RabinDepartment of Psychology, Brooklyn College of The City University of New York, Brooklyn, NY, United States.

Funding

Measuring neurodevelopmental effects of polygenic risk for Alzheimer's disease via longitudinal study of brain and cognitive variables in periadolescent childrenR01AG064247 · NIA · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI WARREN, DAVID E · 2019 to 2023
$3.0M
NIA NIH HHS R01 AG064247
6 · The paper itself

Abstract

Background: Real-world decision-making often relies on practical judgment-the ability to evaluate information, anticipate consequences, and respond in an adaptive manner. Despite its importance for preserving independence in aging, this construct is understudied in older adults without dementia. Moreover, there is a gap in knowledge about the association of objective and informant-rated measures of judgment and other variables that impact everyday functioning such as scam vulnerability and white matter integrity, given that structural white matter changes may precede objective cognitive decline. Methods: Community-dwelling older adults classified as cognitively unimpaired (CU; Results: Greater structural connectivity of the UF in right temporal-frontal and frontal-frontal regions was significantly associated with better informant-reported judgment in the overall sample. Better objective and informant-based practical judgment scores were significantly associated with lower informant-reported scam engagement. Objective and informant-rated judgment abilities were significantly worse among participants with MCI compared to CU. Conclusion: Findings highlight the value of using objective and informant sources to capture real-world judgment ability, with implications for the prevention of harmful outcomes. Our results also suggest that structural connectivity within the UF may be a promising biomarker of impaired judgment in older adults without dementia.

Indexed as

decision-makingpractical judgmentscam susceptibilitystructural connectivitywhite matter changes

Identifiers

PMID41853832
PMCPMC12992289

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.