Evidence map›Paper›PMID 41853812›Full record

ReviewNeuro-oncology advances

A systematic review and meta-analysis of outcomes following active surveillance, surgery and radiotherapy of meningiomas in NF2-related schwannomatosis.

Jack Sheppard, Siddarth Kannan, Jane Halliday, Scott Rutherford, Tim Lavin, Claire Forde, Miriam J Smith, Gareth Evans, Andrew T King, Abdurrahman I Islim and 1 more

Abstract readReview
In one paragraph

Review in Neuro-oncology advances. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Jack SheppardManchester Centre for Clinical Neurosciences, Salford Royal Hospital, Manchester, UK.ORCID https://orcid.org/0009-0002-3067-5116
Siddarth KannanUCLan School of Medicine & Dentistry, University of Central Lancashire, Preston, UK.ORCID https://orcid.org/0009-0004-8703-4859
Jane HallidayManchester Centre for Clinical Neurosciences, Salford Royal Hospital, Manchester, UK.ORCID https://orcid.org/0000-0003-0945-5143
Scott RutherfordManchester Centre for Clinical Neurosciences, Salford Royal Hospital, Manchester, UK.ORCID https://orcid.org/0000-0002-6749-2295
Tim LavinManchester Centre for Clinical Neurosciences, Salford Royal Hospital, Manchester, UK.
Claire FordeGeoffrey Jefferson Brain Research Centre, Northern Care Alliance NHS Foundation Trust, Manchester, UK.ORCID https://orcid.org/0000-0001-8035-4471
Miriam J SmithGeoffrey Jefferson Brain Research Centre, Northern Care Alliance NHS Foundation Trust, Manchester, UK.ORCID https://orcid.org/0000-0002-3184-0817
Gareth EvansGeoffrey Jefferson Brain Research Centre, Northern Care Alliance NHS Foundation Trust, Manchester, UK.ORCID https://orcid.org/0000-0002-8482-5784
Andrew T KingManchester Centre for Clinical Neurosciences, Salford Royal Hospital, Manchester, UK.ORCID https://orcid.org/0000-0002-6546-7248
Abdurrahman I IslimManchester Centre for Clinical Neurosciences, Salford Royal Hospital, Manchester, UK.ORCID https://orcid.org/0000-0001-9621-043X
Omar N PathmanabanManchester Centre for Clinical Neurosciences, Salford Royal Hospital, Manchester, UK.ORCID https://orcid.org/0000-0002-5083-9416

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Meningiomas affect up to 80% of patients with Methods: Systematic review and meta-analysis conducted using the PRISMA framework. Six databases were searched from inception to September 2025. Patient demographics, intervention data, and outcomes were collected and pooled analyses performed. Studies were appraised using the NIH quality assessment tool. Results: Fifteen studies with 937 patients and 3637 meningiomas were included. The pooled proportion of female patients was 59.6% (95% confidence interval [CI]: 55.4-63.7). A total of 2082 tumors were monitored (mean follow-up 5.55-9.18 years) with a weighted mean growth rate of 0.508 cm Conclusion:

Indexed as

active monitoringmeningiomaNF2-related schwannomatosisstereotactic radiosurgerysurgery

Identifiers

PMID41853812
PMCPMC12994695

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.