Evidence map›Paper›PMID 41853719›Full record

ArticleFrontiers in microbiology2026

Antibody response induced by structural proteins from

Aline Maria Vasconcelos Queiroz, Annamairlla do Nascimento Oliveira, Alzira Regina Silva de Deus, Ingrid Emiliane Fonseca de Oliveira, Isaías Amâncio Dos Santos, Fred Luciano Neves Santos, Paola Alejandra Fiorani Celedon, Diego M A Guérin, Ana Rosa Viguera, Marcelo Sousa-Silva

Abstract read
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In one paragraph

Article in Frontiers in microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Aline Maria Vasconcelos Queiroz *Postgraduate Programme in Pharmaceutical Sciences, Federal University of Rio Grande do Norte, Natal, Brazil.
Annamairlla do Nascimento Oliveira *Postgraduate Programme in Pharmaceutical Sciences, Federal University of Rio Grande do Norte, Natal, Brazil.
Alzira Regina Silva de DeusPostgraduate Programme in Pharmaceutical Sciences, Federal University of Rio Grande do Norte, Natal, Brazil.
Ingrid Emiliane Fonseca de OliveiraDepartment of Clinical and Toxicological Analysis, Immunoparasitology Laboratory, Federal University of Rio Grande do Norte, Natal, Brazil.
Isaías Amâncio Dos SantosDepartment of Clinical and Toxicological Analysis, Immunoparasitology Laboratory, Federal University of Rio Grande do Norte, Natal, Brazil.
Fred Luciano Neves SantosAdvanced Public Health Laboratory, Gonçalo Moniz Institute, Fiocruz, Salvador, Brazil.
Paola Alejandra Fiorani CeledonCarlos Chagas Institute, Fiocruz, Curitiba, Brazil.
Diego M A GuérinInstituto Biofisika (UPV/EHU, CSIC), Leioa, Spain.
Ana Rosa VigueraInstituto Biofisika (UPV/EHU, CSIC), Leioa, Spain.
Marcelo Sousa-SilvaPostgraduate Programme in Pharmaceutical Sciences, Federal University of Rio Grande do Norte, Natal, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Virus-Like Particles (VLPs) are viral protein structures widely used as adjuvants in vaccine formulations due to their ability to stimulate the innate immune response, thereby contributing to the activation of adaptive immunity through the production of different IgG subclasses. The present study evaluated the adjuvant potential of recombinant structural proteins of the Methods: BALB/c mice were immunised with native antigens of Leishmania amazonensis or chimeric recombinant antigens of Results and Discussion: Immunisation with

Indexed as

adjuvanthumoral immune responseimmunisation modelsrecombinant proteinsTriatoma virusvaccinevirus-like particles (VLPs)

Identifiers

PMID41853719
PMCPMC12992256

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.