Evidence map›Paper›PMID 41853585›Full record

ArticleResearch and practice in thrombosis and haemostasis2026

Anticoagulation management and monitoring in ECMO: an international survey: communication from the ISTH SSC Subcommittee on Pediatric and Neonatal Thrombosis and Hemostasis.

Katherine Regling, Ronald Thomas, E Vincent S Faustino, Neil A Goldenberg, Meera Chitlur

Abstract read
In one paragraph

Article in Research and practice in thrombosis and haemostasis, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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0cells of the map it votes in
2citing papers in PubMed
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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Observational
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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Katherine ReglingDivision of Hematology Oncology, Department of Pediatrics, Children's Hospital of Michigan, Central Michigan University College of Medicine, Detroit, MI, United States.
Ronald ThomasDepartment of Pediatrics, Children's Hospital of Michigan, Central Michigan University College of Medicine, Detroit, MI, United States.
E Vincent S FaustinoSection of Critical Care Medicine, Department of Pediatrics, Yale School of Medicine, New Haven, CT, United States.
Neil A GoldenbergJohns Hopkins All Children's Institute for Clinical and Translational Research, St. Petersberg, FL and Departments of Pediatrics and Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, United States.
Meera ChitlurDivision of Hematology Oncology, Department of Pediatrics, Children's Hospital of Michigan, Central Michigan University College of Medicine, Detroit, MI, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: The objective of this survey is to assess current practices in anticoagulation management, laboratory monitoring, and hematology involvement in extracorporeal membrane oxygenation (ECMO) patients. Methods: A cross-sectional international survey distributed between April 2023 to November 2023 to members of Hemostasis and Thrombosis Research Society, International Society on Thrombosis and Haemostasis, and Extracorporeal Life Support Organization. Respondents were pediatric and adult physicians involved in the care of ECMO patients. Results: Seventy-two survey responses were included with 83.3% of respondents being from an Extracorporeal Life Support Organization Institution. The respondents included both adult (41.7%) and pediatric (34.7%) physicians, as well as those who managed all age groups (23.6%). Approximately 53% reported including hematology as part of the care team. However, the majority reported that the hematologist is involved in complex cases only (72.2%). Respondents reported the routine utilization of an anticoagulation protocol (92%) and transfusion protocol (83%) to guide management decisions during ECMO therapy; however, management practices were variable. Both unfractionated heparin and bivalirudin were reported to be used routinely for anticoagulation at 92.2% and 52.9%, respectively. Conclusions: This survey demonstrated that hematology involvement for ECMO patients is still primarily for complicated cases. In addition, unfractionated heparin continued to be the anticoagulant of choice, with no significant changes in laboratory monitoring. Most centers utilize protocols for management, yet wide variability in ECMO management was again highlighted. Continued prospective and collaborative research efforts are needed to make advancements in treatment and outcomes, and to help streamline the care of this complex patient population.

Indexed as

anticoagulantsclinical laboratory techniquesECMOsurveytherapeutics

Identifiers

PMID41853585
PMCPMC12993287

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.