Evidence map›Paper›PMID 41853555›Full record

ArticleFrontiers in microbiomes2024

A short-term, randomized, controlled, feasibility study of the effects of different vegetables on the gut microbiota and microRNA expression in infants.

Lynn E Ferro, Kyle Bittinger, Sabrina P Trudo, Kaleigh E Beane, Shawn W Polson, Jae Kyeom Kim, Jillian C Trabulsi

Abstract read
In one paragraph

Article in Frontiers in microbiomes, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Lynn E FerroDepartment of Health Behavior and Nutrition Sciences, University of Delaware, Newark, DE, United States.
Kyle BittingerDivision of Gastroenterology, Hepatology, and Nutrition, Children's Hospital of Philadelphia, Philadelphia, PA, United States.
Sabrina P TrudoSchool of Human Environmental Sciences, University of Arkansas, Fayetteville, AR, United States.
Kaleigh E BeaneSchool of Human Environmental Sciences, University of Arkansas, Fayetteville, AR, United States.
Shawn W PolsonCenter for Bioinformatics and Computational Biology, University of Delaware, Newark, DE, United States.
Jae Kyeom KimDepartment of Health Behavior and Nutrition Sciences, University of Delaware, Newark, DE, United States.
Jillian C TrabulsiDepartment of Health Behavior and Nutrition Sciences, University of Delaware, Newark, DE, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The complementary diet influences the gastrointestinal (gut) microbiota composition and, in turn, host health and, potentially, microRNA (miRNA) expression. This study aimed to assess the feasibility of altering the gut microbial communities with short-term food introduction and to determine the effects of different vegetables on the gut microbiota and miRNA expression in infants. A total of 11 infants were randomized to one of the following intervention arms: control, broccoli, or carrot. The control group maintained the milk diet only, while the other groups consumed either a broccoli puree or a carrot puree on days 1-3 along with their milk diet (human milk or infant formula). Genomic DNA and total RNA were extracted from fecal samples to determine the microbiota composition and miRNA expression. Short-term feeding of both broccoli and carrots resulted in changes in the microbiota and miRNA expression. Compared to the control, a trend toward a decrease in Shannon index was observed in the carrot group on days 2 and 4. The carrot and broccoli groups differed by weighted UniFrac.

Indexed as

ApiaceaebroccolicarrotCruciferaeinfant feedingmicrobiome

Identifiers

PMID41853555
PMCPMC12993569

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.