ReviewJID innovations : skin science from molecules to population health2026
An updated guide to hair follicle stem cell markers and changes in their expression with aging.
Review in JID innovations : skin science from molecules to population health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Hair Follicle Stem Cells: Emerging Physiology and Therapeutic Applications.Stem cell reviews and reports · 2026Review
- Single-Nucleus Transcriptomic Atlas of Human Vellus Hair Pilosebaceous Units Reveals Age-Associated Remodeling.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Particulate matter exposure induces maternal scalp hair loss after birth in C57/B6 mouse via alteration of inflammatory and apoptotic pathways.Frontiers in endocrinology · 2026Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The availability of identification markers is a major expectation in the field of stem and progenitor cell biology, whether to decipher the hierarchy of these cellular compartments or to isolate these cells for use in tissue reconstruction and regeneration approaches. Epithelial hair follicle stem cells (HFSCs) constitute a well-established model of multipotent tissue stem cells. Knowledge of relevant HFSC phenotypes is crucial for their identification and manipulation for therapeutics, including hair regeneration in patients with alopecia and skin engineering after injury. In this review, we provide a detailed review of murine and human HFSC markers, drawing upon traditional studies that identify classic HFSC markers and highlighting single-cell RNA-sequencing studies that have greatly expanded our knowledge of HFSCs. Recently defined HFSC subsets with distinct marker expression, microRNAs that qualify as cycle-specific HFSC markers, and HFSC marker changes with aging are all discussed.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.