ArticleCureus2026
Cutaneous Metastasis From Rectal Adenocarcinoma Mimicking Vegetative Genital Herpes: A Case Report.
Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Authors and funding
4 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Colorectal cancer is the third most common cancer worldwide. Cutaneous metastases are rare and usually represent advanced disease. and their diverse clinical manifestations may mimic inflammatory or infectious dermatoses, leading to delayed diagnosis and poor outcomes. We present a case of a 70-year-old woman with a history of moderately differentiated rectal adenocarcinoma treated with neoadjuvant radiotherapy and surgery who developed metastatic disease with a KRAS G12V mutation. During follow-up, she presented with vulvar, perineal, inguinal, and gluteal erythematous papules, nodules, and simulating vesicles, initially misdiagnosed as an atypical herpetic infection. Histopathological examination of punch biopsies revealed gland-forming malignant epithelial cells consistent with cutaneous metastasis from colorectal adenocarcinoma. Cutaneous metastases from colorectal cancer show heterogeneous and sometimes rare presentations, including herpetiform and pseudotumoral patterns. Vulvar involvement is exceptionally uncommon therefore prompt recognition and histopathological confirmation are essential in patients with persistent or atypical lesions to avoid misdiagnosis and allow timely management.
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