Evidence map›Paper›PMID 41853400›Full record

ArticleCureus2026

Tuberculosis-Associated Hemophagocytic Syndrome Mimicking Malignant Lymphoma: A Case Report.

Yohei Otsuka, Toshinori Nishizawa, Toru Morikawa

Abstract readCase Reports
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Yohei OtsukaDepartment of General Medicine, Aso Iizuka Hospital, Iizuka, JPN.
Toshinori NishizawaDepartment of General Medicine, St. Luke's International Hospital, Tokyo, JPN.
Toru MorikawaDepartment of Data Science, Hyogo Medical University, Nishinomiya, JPN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 78-year-old man presented with prolonged fever, weight loss, erythema, and necrotic lymphadenopathy. Initial suspicion of malignant lymphoma-associated hemophagocytic syndrome (HPS) arose from high Fluorodeoxyglucose (FDG) uptake in lymph nodes on PET/CT. However, lymph node biopsy revealed caseous necrosis and granulomas containing acid-fast bacilli, confirming tuberculosis-associated HPS. Diagnosis was delayed due to a negative interferon-gamma release assay and imaging and clinical features resembling malignancy. This case demonstrates that tuberculosis can act as a great mimicker, often presenting similarly to malignancy and complicating diagnosis. Necrotic lymphadenopathy with peripheral enhancement on CT and overlapping Maximum Standardized Uptake Value (SUV

Indexed as

ct imaging necrosishemophagocytic syndromelymphoma differential diagnosistuberculosistuberculous lymphadenitis

Identifiers

PMID41853400
PMCPMC12993243

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.