Evidence map›Paper›PMID 41853355›Full record

ArticleFrontiers in microbiomes2023

Vaginal microbiota of adolescents and their mothers: A preliminary study of vertical transmission and persistence.

Christine M Bassis, Kaylie A Bullock, Daniel E Sack, Katie Saund, Ali Pirani, Evan S Snitkin, Veronica I Alaniz, Elisabeth H Quint, Jason D Bell, Vincent B Young

Abstract read
In one paragraph

Article in Frontiers in microbiomes, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Observational
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Christine M BassisDepartment of Internal Medicine/Division of Infectious Diseases, University of Michigan Medical School, Ann Arbor, MI, United States.
Kaylie A BullockDepartment of Internal Medicine/Division of Infectious Diseases, University of Michigan Medical School, Ann Arbor, MI, United States.
Daniel E SackDepartment of Internal Medicine/Division of Infectious Diseases, University of Michigan Medical School, Ann Arbor, MI, United States.
Katie SaundDepartment of Microbiology & Immunology, University of Michigan Medical School, Ann Arbor, MI, United States.
Ali PiraniDepartment of Microbiology & Immunology, University of Michigan Medical School, Ann Arbor, MI, United States.
Evan S SnitkinDepartment of Internal Medicine/Division of Infectious Diseases, University of Michigan Medical School, Ann Arbor, MI, United States.
Veronica I AlanizDepartment of Obstetrics and Gynecology, University of Michigan Medical School, Ann Arbor, MI, United States.
Elisabeth H QuintDepartment of Obstetrics and Gynecology, University of Michigan Medical School, Ann Arbor, MI, United States.
Jason D BellDepartment of Obstetrics and Gynecology, University of Michigan Medical School, Ann Arbor, MI, United States.
Vincent B YoungDepartment of Internal Medicine/Division of Infectious Diseases, University of Michigan Medical School, Ann Arbor, MI, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Factors that influence vaginal microbiota composition, including its source, are not well understood. Methods: To determine if vaginal microbiota transmission from mother to daughter at birth could possibly influence the human vaginal microbiota composition in adolescence, we conducted a preliminary study to investigate the relationship between the vaginal microbiota of 13 adolescents (ages 15-21) and their mothers and the daughter's birth mode. Results and discussion: Based on analysis of bacterial 16S rRNA gene sequences, the vaginal microbiotas of mother/daughter pairs were more similar to each other if the daughter was born by vaginal delivery rather than by C-section. Specifically, within pair β-diversity, measured by the Yue and Clayton θ (θYC) distance metric, was significantly lower if the daughter was born by vaginal delivery. Additionally, genome sequences from an important member of the vaginal microbiota,

Indexed as

16S rRNA gene sequencesLactobacillus crispatus genomicsmicrobiomemother-daughter vaginal microbiotavaginal microbiotavertical transmission

Identifiers

PMID41853355
PMCPMC12993637

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.