Evidence map›Paper›PMID 41853297›Full record

ArticleJournal of molecular and cellular cardiology plus2026

Deletion of Cd248 in

Donghua Li, Dongmei Zhong, Tian Tan, Zhilei Huang, Mingyue Wu, Yongshan Liu, Yalin Zhang, Chen Liu, Jie Xu, Fu-Li Xiang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of molecular and cellular cardiology plus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Donghua LiInstitute of Precision Medicine, the First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Dongmei ZhongInstitute of Precision Medicine, the First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Tian TanDepartment of Anesthesia, the First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Zhilei HuangInstitute of Precision Medicine, the First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Mingyue WuInstitute of Precision Medicine, the First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Yongshan LiuInstitute of Precision Medicine, the First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Yalin ZhangInstitute of Precision Medicine, the First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Chen LiuDepartment of Cardiology, the First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Jie XuInstitute of Precision Medicine, the First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Fu-Li XiangInstitute of Precision Medicine, the First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiac fibrosis driven by activated myofibroblasts is a central feature of pressure-overload heart disease. CD248 (Endosialin/TEM1) has been implicated as a pro-fibrotic marker in ischemic cardiac injury, but its role in pressure overload remains unclear. Here, we tested whether selective deletion of Cd248 in Periostin-expressing ( eTOC blurb: In pressure‑overloaded mouse hearts, deleting

Indexed as

Cardiac fibrosisCd248MyofibroblastPeriostinPressure overloadTransverse aortic constriction (TAC)

Identifiers

PMID41853297
PMCPMC12994045

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.