Evidence map›Paper›PMID 41853207›Full record

ArticleRSC advances2026

A structural blueprint for antibacterial discovery: microwave- and ultrasound-assisted synthesis of pyrrolidine-fused quinoxalines as novel inhibitors of DNA gyrase and biofilm.

Eman A Fayed, Mazin A A Najm, Mostafa I Abdelglil, Triveena M Ramsis, Nirvana A Gohar, Shimaa A Metwally, Maha A Ebrahim

Abstract read
In one paragraph

Article in RSC advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Eman A FayedDepartment of Pharmaceutical Organic Chemistry, Faculty of Pharmacy (Girls), Al-Azhar University Cairo 11754 Egypt alfayed_e@azhar.edu.eg alfayed_e@yahoo.com +202 01221330523.ORCID https://orcid.org/0000-0002-4579-5180
Mazin A A NajmDepartment of Pharmacy, Mazaya University College Nasiriyah 64001 Iraq.
Mostafa I AbdelglilDepartment of Medical Laboratory Techniques, Al-Farahidi University Baghdad 10021 Iraq.
Triveena M RamsisDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, Sinai University Kantara Branch Ismailia 41636 Egypt triveena.farid@su.edu.eg triveenaramsis@gmail.com.
Nirvana A GoharDepartment of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Modern University for Technology and Information (MTI) Cairo 11571 Egypt.ORCID https://orcid.org/0000-0002-6442-7762
Shimaa A MetwallyMicrobiology and Immunology Department Faculty of Pharmacy (Girls), Al-Azhar University Cairo 11754 Egypt.
Maha A EbrahimDepartment of Pharmaceutical Organic Chemistry, Faculty of Pharmacy (Girls), Al-Azhar University Cairo 11754 Egypt alfayed_e@azhar.edu.eg alfayed_e@yahoo.com +202 01221330523.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In order to lessen the severity of infectious diseases, anti-infective agents-drugs that prevent, combat, or control infections brought on by microorganisms-are essential in contemporary medicine. To tackle antimicrobial resistance, this project intends to design and synthesize hybrid compounds that contain pyrrolidine, quinoxaline and a hydrazinyl bridge, and assess the antimicrobial and antifungal properties of these compounds against a variety of pathogenic strains. The bactericidal properties of hybrids 24, 27, and 29 against

Identifiers

PMID41853207
PMCPMC12994725

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.